Topological Approach to Quantitation of Rheumatoid Arthritis

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Hamish Carr, John Ryan, Maria Joyce, Oliver Fitzgerald, Douglas Veale, Robin Gibney, and Patrick Brennan

University College Dublin

Summary. Clinical radiologists require not only visual representations of MRI and CT data but also quantitative measurements representing the progression of chronic conditions such as rheumatoid arthritis of the knee. Since inflammation is confined to a thin irregularly shaped region called the synovial capsule it is necessary to segment a suitable approximation of the capsule, then compute quantitative measurements within the segmented region. We report preliminary results on applying topological tools to identify the desired region visually and to extract quantitative information, along with a protocol for clinical validation of the method.

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Osteoarthritis

Osteoarthritis

Thank you for deciding to learn more about the disorder, Osteoarthritis. Inside these pages, you will learn what it is, who is most at risk for developing it, what causes it, and some treatment plans to help those that do have it feel better. While there is no definitive “cure” for Osteoarthritis, there are ways in which individuals can improve their quality of life and change the discomfort level to one that can be tolerated on a daily basis.

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