Rheumatoid Nodule

A case of tracheal rheumatoid nodules in a 45-year-old Chinese man has been reported.17 The patient had suffered rheumatoid arthritis for 7 years, with articular manifestations and deformities. Subcutaneous rheumatoid nodules had been present over his elbows and hands.

Endoscopy showed four smooth, whitish nodules, each 3 to 5 mm in diameter. Further specification was not possible on endoscopic findings. Histologic examination showed foci of necrobiosis and vascular fibrinoid necrosis in the vessels surrounded by palisading histiocytes.

Among the histologic differential diagnoses are necrotizing granulomatous diseases such as tuberculosis and histoplasmosis. Amyloid deposits must also be separated from central necrobiosis of this lesion, which may have a similar eosinophilic patternless aspect. Amyloid material, however, is more homogeneous, and stains with Congo red and other special histochemical stains.

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Osteoarthritis

Osteoarthritis

Thank you for deciding to learn more about the disorder, Osteoarthritis. Inside these pages, you will learn what it is, who is most at risk for developing it, what causes it, and some treatment plans to help those that do have it feel better. While there is no definitive “cure” for Osteoarthritis, there are ways in which individuals can improve their quality of life and change the discomfort level to one that can be tolerated on a daily basis.

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