1. Progressive disappearance of carpus/tarsus; involvement of adjacent areas; proximal tapering of metacarpals/metatarsals (hereditary multicentric osteolysis with nephropathy)
2. Collapse and resorption of the carpotarsal bones; widening and cortical thinning of tubular bones without proximal tapering; osteoporosis (hereditary multicentric osteolysis of Torg)
3. Early-onset carpotarsal osteolysis; osteopenia; un-dertubulation of bones; sclerotic cranial sutures; brachycephaly; broad medial ends of the clavicles (idiopathic osteolysis, Saudi Arabia type)
4. Progressive carpotarsal osteolysis; elbow osteoly-sis; osteopenia; severe joint contractures (Winchester syndrome)
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