Sweating Ebooks Catalog
Use with caution in lactation, with impaired hepatic function, or if receiving drugs known to influence hepatic metabolism. Safety and efficacy have not been established in children. Side Effects The following side effects are common to alpha-1-adren-ergic blockers. See individual drugs as well. Oral Dry mouth. CV Palpitations, postural hypotension, hypotension, tachycardia, chest pain, arrhythmia. GI N&V, diarrhea, constipation, abdominal discomfort or pain, flatulence. CNS Dizziness, depression, decreased libido, sexual dysfunction, nervousness, paresthesia, somnolence, anxiety, insomnia, asthenia, drowsiness. Musculoskeletal Pain in the shoulder, neck, or back gout, arthritis, joint pain, arthralgia. Respiratory Dyspnea, nasal congestion, sinusitis, bronchitis, broncho-spasm, cold symptoms, epistaxis, increased cough, flu symptoms, pharyngitis, rhinitis. Ophthalmic Blurred vision, abnormal vision, reddened sclera, conjunctivitis. GU Impotence, urinary frequency,...
Side Effects CNS Headache, fatigue, lethargy, somnolence, dizziness, lightheadedness, sleep disturbances, depression, amnesia, psychosis, hallucinations, paresthesia, asthenia, insomnia, abnormal dreams, malaise, anxiety, tremor, hand tremor, hypoesthesia, vertigo, depersonalization, migraine, apathy, agitation, amnesia. Oral Dry mouth, thirst, gingival hyperplasia, altered taste. GI Nausea, abdominal discomfort, cramps, dyspepsia, diarrhea, constipation, vomiting, flatulence, dysphagia, loose stools. CV Peripheral edema, palpitations, hypotension, syncope, bradycardia, unspecified arrhythmias, tachycardia, ventricular extrasystoles, peripheral ischemia, cardiac failure, pulse irregularity, increased risk of MI. Dermatologie Dermatitis, rash, pruritus, urticaria, photosensitivity, pe-techiae, ecchymosis, purpura, bruising, hematoma, cold clammy skin, skin discoloration, dry skin. Musculoskeletal Muscle cramps, pain, or inflammation joint stiffness or pain, arthritis, twitching,...
The afferent arm of these reflexes originates in the internal organs and terminates on the sympathetic preganglionic neurons in the interme-diolateral and intermediomedial cell columns of the spinal cord at levels T1 through L2 (p. 140). Typical examples are the viscerovisceral reflex (causing meteorism in colic and anuria in myo-cardial infarction), the viscerocutaneous reflex (a visceral stimulus leads to sweating and hyper-emia in the corresponding zone of Head), the cutivisceral reflex (reduction of colic, myogelosis, etc., by warm compresses or massage), the visceromotor reflex (defensive muscle contraction in response to visceral stimulus), and the vasodilatory axon reflex (dermographism). Any abnormality of these reflexes may be an important sign of impaired autonomic function (cardiovascular, gastrointestinal, thermoregulatory, or urogenital), particularly in patients with spinal cord disorders.
Pruritic hives, 1 to 3 mm with a large red axon flare, develop after a stimulus that causes sweating. The primary lesions are papules and they may occur at any site, but are most common on the upper torso. Attacks can be triggered by severe stress, exercise, heat exposure, and even hot food. Symptoms can be readily reproduced by exercise or intradermal cholinergic agents. Cholinergic hives show partial response to standard H1 blockers. Transdermal scopolamine or small doses of other oral anticholinergic agents may be helpful.
Naproxen sodium Action Kinetics The antiinflammatory effect is believed to result from the inhibition of the enzyme cyclooxygenase, resulting in decreased prostaglandin synthesis. The agents are effective in reducing joint swelling, pain, and morning stiffness, as well as in increasing mobility in individuals with inflammatory disease. They do not alter the course of the disease, however. Their anti-inflammatory activity is comparable to that of aspirin. The analgesic activity is due, in part, to relief of inflammation. Also, the drugs may inhibit lipoxygenase, inhibit synthesis of leuko-trienes, inhibit release of lysosomal enzymes, and inhibit neutrophil aggregation. Rheumatoid factor production may also be inhibited. The antipyretic action occurs by decreasing prostaglandin synthesis in the hypothalamus, resulting in an increase in peripheral blood flow and heat loss as well as promoting sweating. NSAIDs also inhibit miosis induced by prosta-glandins during the course of cataract...
Side Effects CV Bradycardia, postural hypotension, dependent or peripheral edema, AV block, extrasystoles, hypertension, hypotension, palpitations, peripheral ischemia, syncope, angina, cardiac failure, myocardial ischemia, tachycardia, CV disorder. CNS Dizziness, headache, somnolence, insomnia, ataxia, hypesthesia, paresthesia, vertigo, depression, nervousness, migraine, neuralgia, paresis, amnesia, confusion, sleep disorder, impaired concentration, abnormal thinking, paranoia, emotional lability. Body as a whole Fatigue, viral infection, rash, allergy, asthenia, malaise, pain, injury, fever, infection, somnolence, sweating, sudden death. Oral Dry mouth. GI Diarrhea, abdominal pain, biliru-binemia, N&V, flatulence, anorexia, dyspepsia, melena, periodontitis, increased hepatic enzymes, GI hemorrhage. Respiratory Rhinitis, pharyngitis, sinusitis, bronchitis, dyspnea, asthma, bronchospasm, pulmonary edema, respiratory alkalosis, dyspnea, respiratory disorder, URTI, coughing. GU UTI,...
Orthostatic after prolonged bed rest On antihypertensives or dialysis Auto-nomic abnormalities diabetes, nocturnal diarrhea, impotence, peripheral neuritis, or absent sweating Worse if hot or fatigued Large varicose veins 1. Coronary obstruction classic angina precipitated mainly after first exertion in morning, by food or cold air and anything that increases heart rate or afterload. With pallor, flatulence, nausea, sweating, or dyspnea Relieved by drugs that decrease preload, afterload, heart rate, or inotropism Risk factors diabetes, hypertension, artificial menopause, contraceptive use, smoking, gout, intermittent claudication, previous infarction, family history of coronary disease, increased cholesterol or low HDL
Hematologic Leuko-penia, granulocytopenia, thrombo-cytopenia, microcytic anemia, hemorrhage, ecchymosis, petechiae. Der-matologic Rash, pruritus, herpes simplex, skin disorder, sweating, eczema, impetigo, excoriation, erythema. Musculoskeletal Asthenia, myo-pathy, arthralgia, arthritis, myalgia, muscle atrophy, decreased strength, hemiparesis, neck rigidity, joint disorder, leg cramps. CV Chest pain, hypertension, hypotension, migraine, palpitation, peripheral vascular disorder, syncope, vasodilation, arrhythmias. Body as a whole Chills, fever, infection, allergic reaction, pain, abscess, cellulitis, cyst, dehydration, malaise, flu syndrome, numbness of hands and feet, weight loss, alopecia. Respiratory Pneumonia, dyspnea, asthma, bronchitis, increased cough, rhinitis, rhinorrhea, epistaxis, laryngitis, decreased lung function, pharyngitis, hypoventilation, sinusitis, rhonchi, rales, congestion, interstitial pneumonia, respiratory disorders. Ophthalmic Blurred vision,...
doped-up sensation, suicidal tendencies, psychoses. Oral Dry mouth and throat, dental abnormalities, gingivitis, glossitis, gum hemorrhage, stomatitis, taste loss, unusual taste, increased salivation. GI Most commonly N&V. Also, dyspepsia, constipation, increased appetite, abdominal pain, diarrhea, anorexia, flatulence, thirst, gastroenteritis, hemorrhoids, bloody stools, fecal incontinence, hepatomegaly. CV Hypertension, vasodilation, hypotension, angina pectoris, peripheral vascular disorder, palpitation, tachycardia, migraine, murmur. Musculoskeletal Myalgia, fracture, tendinitis, arthritis, joint stiffness or swelling, positive Romberg test. Respiratory Rhinitis, pharyngitis, coughing, pneumonia, epistaxis, dyspnea, ap-nea. Dermatologie Pruritus, abrasion, rash, acne, alopecia, eczema, dry skin, increased sweating, urticaria, hirsutism, seborrhea, cyst, herpes simplex. Body as a whole Weight increase, back pain, peripheral edema, asthenia, facial edema, allergy, weight decrease,...
Uses Can relieve nervousness, dysentery, constipation, excessive sweating, diarrhea, abdominal pain, intestinal paralysis. Traditional Name Jian Zhen Shoulder Chastity Location On the back, just above the armpit. Uses Can relieve shoulder problems, paralysis of the upper limbs, excessive perspiration in the armpits, pain in the shoulder blades, toothaches, deafness, swelling of the joints.
This commonest form of LS is defined by the presence of lesions 1cm in diameter, occurring in 1 or 2 anatomical sites (Peterson et al. 1995 & 1997). The trunk is the most commonly involved site (41-74 patients), but plaques can occur anywhere, including the face and neck (12-13 of patients) (Christi-anson et al. 1956 Peterson et al. 1997). Onset is usually slow and insidious. Circumscribed oval patches may be erythematous and oedematous in the earliest stages, becoming indurated, yellowish-white or ivory coloured (Figure 2a). A surrounding violaceous halo, the lilac ring , suggests active inflammation, but was documented in only 43 of patients in one study (Peterson et al. 1997). The patches subsequently become waxy, shiny and sclerotic. Over months to years they soften, become atrophic and hypo- or hyperpigmented. Atrophy may involve the epidermis, dermis and or subcutaneous tissue, producing wrinkling or depression of the skin surface. Lesions may be pruritic and or paraesthetic....
Side Effects Oral Dental pain, dry mouth. GI Diarrhea, dyspepsia, anorexia, constipation, flatulence, gastritis, vomiting, taste perversion. CV Angina pectoris, second-degree AV block, CVA, MI, ventricular tachycardia, ventricular fibrillation, hypotension, palpitation, sinus bradycardia, tachycardia, orthostatic effects. CNS Dizziness, insomnia, anxiety, anxiety disorder, ataxia, confusion, depression, abnormal dreams, hypesthesia, decreased libido, impaired memory, migraine, nervousness, paresthesia, peripheral neuropathy, panic disorder, sleep disorder, somnolence, tremor, vertigo. Respiratory Upper respiratory infection, cough, nasal congestion, sinus disorder, sinusitis, dyspnea, bronchitis, pharyngeal discomfort, epistaxis, rhinitis, respiratory congestion. Musculoskeletal Muscle cramps, myalgia, joint swelling, musculoskeletal pain, stiffness, arthralgia, arthritis, fibromyalgia, muscle weakness pain in the back, legs, arms, hips, knees, shoulders. Dermatologic Alopecia,...
Musculoskeletal Arthralgia, arthritis, cramps, myalgia, myasthenia, myopathy. Dermatologic Dermatitis, folliculitis, fungal dermatitis, macu-lopapular rash, pruritus, urticaria, sweating. Miscellaneous Asthenia, dehydration, allergic reaction, back pain, fever, headache, malaise, pain, accidental injury.
Abnormal thinking, akinesia, alcohol abuse, ataxia, convulsions, possibility of a suicide attempt depersonalization, hallucinations, hyperkinesia, hyper-tonia, incoordination, lack of emotion, manic reaction, paranoid reaction. Oral Dry mouth, dysphagia, glossitis, increased salivation, mouth ulceration. GI Nausea, abdominal pain, diarrhea, vomiting, constipation, decreased appetite, flatulence, oropharynx disorder ( lump in throat, tightness in throat), dyspepsia, increased appetite, bruxism, eructation, gastritis, rectal hemorrhage, abnormal LFTs. Hematologic Anemia, leu-kopenia, lymphadenopathy, purpura. CV Palpitation, vasodilation, postural hypotension, hypertension, syncope, tachycardia, bradycardia, conduction abnormalities, abnormal ECG, hypotension, migraine, peripheral vascular disorder. Dermatologic Sweating, rash, pruritus, acne, alopecia, dry skin, ecchymosis, eczema, furunculosis, urticaria. Metabolic Nutritional Edema, weight gain, weight loss, hyperglycemia, peripheral...
In an open trial 120 patients undergoing elective hepatic resection were randomized to receive postoperative intravenous patient-controlled analgesia with morphine either alone or in combination with nefopam (20 mg 4-hourly) or propacetamol (2 g 6-hourly) (2). Nefopam plus morphine was the most effective treatment. Adverse effects, especially sedation, were comparable in the three groups, but there was significantly more nausea in the morphine group and more sweating in the nefopam group (requiring early drug withdrawal in three cases). Tachycardia was seen more often in the nefopam group but did not reach significance.
Adverse effects (gastrointestinal effects and sweating) were significantly higher. In a comparison of the analgesic effects of intermittent boluses of tramadol or morphine after abdominal surgery in 523 patients, tramadol caused more adverse effects (43 versus 34 ), although the difference was not statistically significant. The commonest adverse effects were nausea (32 and 22 ), vomiting (4.9 and 3.8 ), urinary retention (3.0 and 2.7 ), and sweating (3.8 and 0.4 ) (SEDA-20, 81).
The use of tramadol for postoperative analgesia by intravenous patient-controlled analgesia (PCA) has gained popularity, mostly because it is less likely to cause sedation and respiratory depression (28). However, it is associated with nausea, vomiting, dry mouth, and sweating. The addition of droperidol to tramadol PCA reduced the incidence of gastrointestinal symptoms without significantly increasing sedation (29). In a double-blind, randomized study, 40 patients undergoing coronary artery bypass grafting and or valve replacement surgery were given droperidol 0.1 mg ml plus either tramadol 10 mg ml or morphine 1 mg ml. The results in the two groups were comparable in efficacy, adverse effects profiles, and dose requirements, and the authors argued that there may be no advantage in using tramadol rather than morphine in conjunction with droperidol (30).
A unilateral small pupil is commonly due to underactivity of the ipsilateral sympathetic pathways. Miosis is commonly associated with ptosis (lid droop) due to sympathetic denervation of the tarsal muscle and facial anhidrosis (loss of sweating). This combination is known as Horner's syndrome. Oculosympathetic paralysis occurs ipsilaterally owing to (1) central lesions involving the hypothalamospinal pathways at the dorsolateral brain stem tegmentum (e.g., a lateral medullary infarct) (2) preganglionic lesions (e.g., compression of the sympathetic chain by a tumor in the apex of the lung) or (3) postganglionic lesions at the level of the internal carotid plexus (e.g., lesions of the cavernous sinus). Postganglionic Horner's syndrome does not result in facial anhidrosis because pupilodilator and sudomotor axons follow separate paths along branches of the internal and external carotid arteries, respectively. FACIAL HYPERHIDROSIS AND FLUSHING Facial flushing may result...
Anxiety The unpleasant emotional state consisting of psychophysiological responses to anticipation of unreal or imagined danger, ostensibly resulting from unrecognized intrapsychic conflict. Physiological concomitants include increased heart rate, altered respiration rate, sweating, trembling, weakness, and fatigue psychological concomitants include feelings of impending danger, powerlessness, apprehension, and tension. eu
Acrocyanosis A condition marked by symmetrical cyanosis of the extremities, with persistent, uneven, mottled blue or red discoloration of the skin of the digits, wrists, and ankles and with profuse sweating and coldness of the digits. Called also Raynaud's sign. eu Hyperhidrosis Excessive perspiration. Called also hyperidrosis, polyhidrosis, and polyidrosis. eu
The answer is a Fauci 14e p 504 Tierney 39e p 650 Vitamin C may cause a falsenegative test The falsepositive rate for
The answer is d. (Goldman, 21 e, pp 51-54. Tintinalli, 5 e, pp 1125-1129.) This patient with underlying liver disease probably has fulminant hepatitis from acetaminophen toxicity. Because of his alcohol use, he has insufficient glutathione stores and induced P450 enzymatic activity and is at greater risk for developing toxicity. Patients who survive the complication of fulminant hepatic failure will begin to recover over the following week, but some require liver transplantation. A serum acetaminophen level should be sent and immediate treatment with N-acetylcysteine (NAC), which provides cysteine for glutathione synthesis, is indicated. Signs of alcohol intoxication include euphoria, dysarthria, ataxia, labile mood, lethargy, coma, respiratory depression, and death. Patients with alcohol withdrawal present with a hyperexcitable state (i.e., hypertension, tachycardia, flushing, sweating, and mydriasis) and have tremors, disordered perceptions, seizures, and delirium tremens...
On mental status examination, the patient stated that he felt he was no longer able to manage his finances. He had lost interest in his usual activities and had a constant fear of dying. The patient also complained of physical symptoms, such as mucous in his throat which made it difficult to swallow and caused respiratory distress. The patient also complained of light-headedness, sweating, and cramps in his stomach associated with anxiety. The patient also had difficulty making decisions and trouble falling asleep as well as frequent awakening during the night and terminal insomnia. He also noted a decrease in his appetite with an 8 lb (3.6 kg) weight loss during the past month.
Pain and sensory loss in 1st and 2nd trigeminal divisions, maximal around the eye and associated with a sympathetic paresis (ptosis and small pupil). Sweating in the lower face is preserved. This may be associated with involvement of the other cranial nerves (IV & VI). The syndrome occurs with lesions of the middle fossa, e.g. nasopharyngeal carcinoma, granulomas and infection.
Pausal women, during lactation, or in pediatric clients. Concurrent use with systemic estrogen or hormone replacement therapy. Special Concerns Use with caution with highly protein-bound drugs, including clofibrate, diaze-pam, diazoxide, ibuprofen, indo-methacin, and naproxen. Effect on bone mass density beyond 2 years of treatment is not known. Side Effects CV Hot flashes, migraine. Body as a whole Infection, flu syndrome, chest pain, fever, weight gain, peripheral edema. CNS Depression, insomnia. GI Nausea, dyspepsia, vomiting, flatulence, GI disorder, gastroenteritis. GU Vaginitis, urinary tract infection, cystitis, leukorrhea, endometrial disorder. Respiratory Sinusitis, pharyngitis, increased cough, pneumonia, laryngitis. Musculoskeletal Arthral-gia, myalgia, leg cramps, arthritis. Dermatologic Rash, sweating. Drug Interactions Ampicillin l Absorption of ampi-cillin
Dizziness, and sweating, to fatigue, depression, and ototoxicity. Less common reactions include pruritus and a variety of dermatological problems. A few instances of jaundice, impairment of renal function, angioedema, thrombocytopenia, and agranulocytosis have been reported.
Respiratory Bronchitis, cough, dyspnea, epistaxis, hemoptysis, laryngitis, pharyngitis, pneumonia, respiratory disorder rhinitis, sinusitis, URTI. GU Enlarged prostate, vaginal discharge, micturition disorder, UTI. Dermatologie Acne, dermatitis, seborrheic dermatitis, eczema, erythema, folliculitis, furunculosis, hair changes, hot flushes, photosensitivity reaction, changes in skin pigment, maculopapular rash, skin disorder, skin nodules, skin ulceration, increased sweating, urticaria, verruca, xeroderma. Ophthalmic Dry eye syndrome, xerophthalmia, blepharitis, eye irritation, visual disturbance. Otie Earache, ear pressure, decreased hearing, otitis, tinnitus. Drug Interactions Astemizole Possibility of prolongation of QT intervals serious CV adverse effects
Retention, kidney calculus, enlarged uterine fibroids, vaginal moniliasis, vaginitis. Hematologic Ecchymosis, anemia, leukopenia, leukocytosis. Musculoskeletal Myasthenia, back pain, pathological fracture, arthral-gia, arthritis, bursitis. Respiratory Sinusitis, pneumonia, bronchitis, rhinitis. Dermatologic Rash, sweating, skin ulcer, pruritus, dry skin, acne, alopecia, urticaria. Body as a whole Flu syndrome, weight loss, infection, sepsis, cellulitis, death, allergic reaction, moniliasis, malaise, asthenia, fever, abscess, edema. Ophthalmic Glaucoma, amblyopia, conjunctivitis, eye pain, optic neuritis, retinal hemorrhage, visual field defect. Otic Ear pain, tinnitus, deafness, otitis media. Miscellaneous Speech disorder.
Occasionally, trigger points produce autonomic nervous system changes such as flushing of the skin, hypersensitivity of areas of the skin, sweating in areas, or even goose bumps. The trigger points cause localized pain, although trigger points can involve the whole body.
Physicians traditionally attacked the gout with bleeding, sweating, purges, cathartics, emetics, diuretics, blisters, massage, and cauterization. From his own experience, Sydenham could testify that none of these methods worked any better than ancient Roman charms and incantations. Abstinence in diet and drink was advisable, but in Sydenham's experience ''If you drink wine you get gout if you do not, gout gets you '' In 2004, scientists actually corroborated the traditional belief that alcohol consumption increases the risk of developing gout. Sydenham would be surprised to learn, however, that beer is more likely to lead to gout than liquor, or wine.
Analogue of the natural compound arecoline, is reported to improve cognition both in animal models and in AD patients, and antagonists of central presynaptic M2 receptors, which include analogues of the naturally derived himbacine (3), also enhance cognitive ability by increasing the release of ACh (1) 22 . To date, treatment with compounds that directly interact with muscarinic receptors has not been a major approach to alleviate cognitive disorders such as AD, perhaps due to the unpleasant cholinergic side-effects such as gastrointestinal contraction and sweating, reported to be associated with muscarinic receptor modulators. Derivatives of arecoline have been synthesised in order to improve selectivity for cortical muscarinic receptors. Examples of arecoline derivatives include xanomeline (2), reported to be functionally selective for the Mi receptor 22 , which delayed cognitive decline and reduced hallucinations and delusions when given to AD patients 116 . Other derivatives of...
Vasodepressor syncope is generally precipitated by a strong emotional response, such as fear or pain. Usually it occurs when a person is already sitting or standing and is often accompanied by a feeling of weakness or sweating beforehand. In order for a cardiac arrhythmia to cause syncope, the heart rate must be generally less than 40 or greater than 180 bpm. It is usually associated with known cardiac disease. An hysterical faint is usually a symbolic expression of an unacceptable idea through the body language of fainting. It is usually seen in people with hysterical personality traits.
Action Kinetics Aspirin manifests antipyretic, anti-inflammatory, and analgesic effects. The antipyretic effect is due to an action on the hypothalamus, resulting in heat loss by va-sodilation of peripheral blood vessels and promoting sweating. The anti-inflammatory effects are probably mediated through inhibition of cyclo-oxygenase, which results in a decrease in prostaglandin synthesis and other mediators of the pain response. The mechanism of action
Two studies have described patients' and spouses' perceptions of the affected partners' sexual function and aspects of the couples' relationship.45 Thirty-six men and 14 women with PD, and their spouses, were recruited from a movement disorder clinic for participation in an investigation of the relationship of autonomic nervous system (ANS) dysfunction, depression, medication, motor disabilities, and sexual difficulties.4 Patients and their spouses completed separate, self-report questionnaires. The patients were asked to answer the Geriatric Depression Scale (GDS),35 a questionnaire of degree of sexual interest, arousal, and performance skills,36 a medical history, a medication history, ANS function (increased sweating, constipation, or urinary difficulties). Spouses completed a questionnaire that addressed sexual interest, arousal, and performance of the affected spouse as well as their own sexual interests.
Prerenal azotemia should be suspected in all conditions characterized by hypovolemia such as hemorrhage, gastrointestinal, renal, or skin losses, and capillary leak. Clinical assessment includes symptoms of thirst and evidence of orthostatic hypotension and tachycardia, decreased skin turgor, dry mucous membranes, and reduced axillary sweating. Definitive diagnosis cames from prompt resolution of acute renal failure after expansion of extracellular fluid volume. Prerenal azotemia may also be encountered in clinical conditions such as nephrotic syndrome and hepatic or cardiac failure, characterized by decreased effective plasma volume clinical examination may reveal signs of chronic liver disease, advanced cardiac failure, and nephrotic syndrome.
Action Kinetics Acetaminophen decreases fever by an effect on the hypothalamus leading to sweating and vasodilation. It also inhibits the effect of pyrogens on the hypothalam-ic heat-regulating centers. It may cause analgesia by inhibiting CNS prostaglandin synthesis however, due to minimal effects on peripheral prostaglandin synthesis, acetaminophen has no anti-inflammatory or uricosuric effects. It does not cause any anticoagulant effect or ulceration of the GI tract. The antipyretic
Acromegaly A syndrome due to excessive formation of growth hormone (GH) by a tumor in the pituitary gland and characterized by coarse facial features, enlargement of hands and feet, headache, sweating, neuropathy, sleep apnea, and musculoskeletal symptoms. Acromegaly affects 40 to 60 people per million population.
He was an outstanding Qigong master. He had high education. He had done a lot of research on Qigong. He knew what he was doing. His master was the chief of the Shaolin Temple at that time. So I gave up myself again. I was sweating, bearing all these unbearable sensations in my body.
Special Concerns Use with caution in presence of ulcers or in clients with a history thereof, in clients with hypertension, compromised cardiac function, or in conditions leading to fluid retention. Use with caution in only first two trimesters of pregnancy. Geriatric clients may be at greater risk of GI toxicity. Side Effects GI Nausea, dyspepsia, GI pain and bleeding, diarrhea, vomiting, constipation, flatulence, peptic ulcer, eructation, anorexia. CNS Headache, fatigue, fever, malaise, dizziness, somnolence, insomnia, nervousness, vertigo, depression, paresthesias. Dermatologic Rashes, pruritus, sweating, Stevens-Johnson syndrome, dry mucous membranes, erythema multiforme. CV Palpitations, syncope, edema. Other Tinnitus, asthenia, chest pain, hyper-
Penia, bone marrow depression, decreased H&H in hypertensive or CHF clients. Hemolytic anemia, including hemolysis, in clients with G6PD deficiency. Dermatologic Rash, pruritus, alopecia, flushing, erythema multiforme, exfoliative dermatitis, photosensitivity, urticaria, increased sweating, pemphigus, Stevens-Johnson syndrome, herpes zoster, toxic epidermal necrolysis. Other Angioedema, asthenia, impotence, blurred vision, fever, arthralgia, arthritis, vasculitis, eosinophilia, tinnitus, syncope, myalgia, rhinorrhea, sore throat, hoarseness, conjunctivitis, tearing, dry eyes, loss of sense of smell, hearing loss, peripheral neuropathy, anosmia, myositis, flank pain, gynecomastia.
Special Concerns Use with caution during lactation. Safety and efficacy have not been established in children. Geriatric clients may manifest higher blood levels. Dosage should be reduced in clients with impaired renal function. Side Effects CNS Dizziness, headache, fatigue, vertigo, insomnia, depression, sleepiness, paresthesias, malaise, nervousness, confusion. Oral Dysgeusia, dry mouth. GI Diarrhea, N&V, dyspepsia, anorexia, constipation, abdominal pain, flatulence. Respiratory Cough, dyspnea, bronchitis, upper respiratory symptoms, nasal congestion, sinusitis, pharyngeal pain, bronchospasm, asthma. CV Hypotension, orthostatic hypotension, angina, tachycardia, palpitations, rhythm disturbances, stroke, chest pain, orthostatic effects, peripheral edema, MI, CVA. Musculos-keletal Asthenia, muscle cramps, joint pain, shoulder and back pain, myalgia, arthralgia, arthritis. Hepatic Hepatitis, cholestatic jaundice, pancreatitis. Dermatologic Rash, pruritus, flushing, increased sweating,...
Assessment (2) After determining which segments are affected, you should try to form an opinion as to the type of injury. This may he difficult to clarify, but the more evidence there is of proximal damage, the greater the chance of cord avulsion and a poor prognosis. Horner's syndrome, characterized by (A) pseudoptosis, (B) smallness of the pupil on the affected side, and (C) dryness of the hand from absence of sweating, occurs when the T1 root is involved close to the canal.
The lower trunk of the brachial plexus and the subclavian artery pass between the anterior and middle scalene muscles and over the first rib. Compression of these structures may result from a cervical rib, a definite but rare occurrence. Slightly more commonly, the same structures may be kinked by fibrous bands or abnormalities in the scalene attachments at the root of the neck, or by a Pancoast tumour. Paraesthesia in the hand is usually severe, and there may be hypothenar and, less commonly, thenar wasting. There is sometimes sympathetic disturbance, with increased sweating of the hand. The radial pulse may be absent, and other signs of vascular impairment may be present. Complete vascular occlusion, sometimes accompanied by thrombosis and emboli, may lead to gangrene of the fingertips. In some cases symptoms may be precipitated by loss of tone in the shoulder girdle, with drooping of the shoulders in such cases, physiotherapy is often successful in restoring tone to the affected...
A herbal record lists the following adverse effects of Ku shen salivation, abnormal gait, dyspnea, tachycardia (71). In larger doses, nervous system stimulation with muscle spasm and seizures can occur. There have been three reports of adverse reactions such as nausea, vomiting, dizziness, bradycardia, palpitation, ataxia, pallor, sweating, seizures, and dysphasia.
Unwanted pentazocine actions include rapid heartbeat, blood pressure changes (up or down), fainting, sweating, confusion, sleepiness, blurred vision, nausea, vomiting, and constipation. Studies have found that 1 to 10 of persons receiving the drug (especially an injectable pharmaceutical version) have odd psychological reactions such as hallucinations, delusions, or a sense of unreality about the world. The substance can interfere with decision making and physical movement. Research has shown that driving skills decline when a person uses the drug, and users should avoid operating motor vehicles or other dangerous machinery. Because pentazocine has occasionally been associated with seizures, it should be used cautiously by persons prone to that affliction. The substance should also be used cautiously by people suffering from pancreas malfunction or breathing difficulty. The drug may be particularly hazardous for asthma sufferers who are overly sensitive to aspirin....
Side Effects First-dose effect Marked postural hypotension and syncope. CV Palpitations, tachycardia, postural hypotension, syncope, arrhythmias, chest pain, vasodilation. CNS Dizziness, headache, somnolence, drowsiness, nervousness, pares-thesia, depression, anxiety, insomnia, vertigo. Respiratory Nasal congestion, dyspnea, sinusitis, epistaxis, bronchitis, bronchospasm, cold or flu symptoms, increased cough, pharyngitis, rhinitis. Oral Dry mouth. GI Nausea, constipation, diarrhea, dyspepsia, vomiting, flatulence, abdominal discomfort or pain. Musculoskeletal Asthenia, arthritis, arthralgia, myalgia, joint disorders, back pain, pain in extremities, neck and shoulder pain, muscle cramps. Miscellaneous Peripheral edema, weight gain, blurred vision, impotence, chest pain, fever, gout, pruritus, rash, sweating, urinary frequency, UTI, tinnitus, conjunctivitis, abnormal vision, edema, facial edema. Drug Interactions Indomethacin l Effects of terazo-sin
Cinchonism describes the toxic state induced by excessive plasma levels of free quinine. Symptoms include sweating, ringing in the ears, impaired hearing, blurred vision, nausea, vomiting, and diarrhea. Quinine is a potent stimulus to insulin secretion and irritates the gastrointestinal mucosa. Also, a variety of relatively rare hematological changes occur, including leukopenia and agranulocytosis. Quinine is potentially neurotoxic in high dosages, and severe hypotension may follow its rapid intravenous administration.
Relapsing fever, 276-77 rubella, 286 scarlet fever, 288-89 smallpox, 301-2 sporotrichosis, 131 sweating sickness, 276, 311-12 trachoma, 233-34 trypanosomiasis, 10-13 tuberculosis, 339-40, 342 typhus, 275, 282-83, 353-55 yellow fever, 365-69 epidemic typhus, 275, 282-83, 353-55 epidemic yellow fever, 365-69. See also yellow fever Epidermophyton, 129 Epidermophyton floccosum, 129 epilepsy, 31, 111, 116-19 Epstein-Barr virus, 162, 174-75 equine encephalitis, 115, 173 equine rabies, 270 ergot intoxication, 288 ergotism, 120-21 characteristics, 120 gangrene in, 136-37 history, 120-21 as Plague of Athens, 252-53 Saint Anthony's fire in, 287-88 sweating sickness and, 312 erosive arthritis, 42. See also arthritis erosive inflammatory osteoarthritis, 235 erosive joint disease, 41 erysipelas, 121-22, 136, 257, 288, 304-5 erysipelas grave internum, 122 erythema, 208 sudden infant death syndrome, 306 sweating sickness, 311-312 syphilis, 314-316, 318 tapeworm infection, 320 Tay-Sachs disease,...
Intramuscular iron injections are often painful, can produce topical discoloration of the skin, and some local inflammation with lymphadenopathy. Rarely, more severe local reactions follow (SEDA-6, 224), such as transient lipomyodystrophy. An unpleasant metallic taste in the mouth is common and can persist for some hours or days. Some patients develop general symptoms, such as headache, flushing, sweating, nausea, vomiting, dizziness, generalized aches and pains, malaise, arthralgia, palpitation, and pericardial or abdominal pain. Although very rare, a severe anaphylactic reaction to intramuscular iron dextran can occur.
Mild chronic salicylate intoxication is called salicylism. When fully developed, the syndrome includes headache, dizziness, tinnitus, difficulty hearing, dimness of vision, mental confusion, lassitude, drowsiness, sweating, thirst, hyperventilation, nausea, vomiting, and occasionally diarrhea.
The answer is b. (Greenfield, 2 e, pp 919-923.) Tumors arising from the pancreatic beta cells give rise to hyperinsulinism. Seventy-five percent of these tumors are benign adenomas in 15 of affected patients the adenomas are multiple. Symptoms relate to a rapidly falling blood glucose level and are due to epinephrine release triggered by hypoglycemia (sweating, weakness, tachycardia). Cerebral symptoms of headache, confusion, visual disturbances, convulsions, and coma are due to glucose deprivation of the brain. Whipple's triad summarizes the clinical findings in patients with insulinomas (1) attacks precipitated by fasting or exertion (2) fasting blood glucose concentrations below 50 mg dL (3) symptoms relieved by oral or intravenous glucose administration. These tumors are treated surgically simple excision of an adenoma is curative in the majority of cases.
The systemic symptoms of brucellosis dominate. The condition often presents as a fever of unknown cause with sweating, loss of weight, arthralgia (joint pains), myalgia (muscle pain), and headache. The arthritis can affect one or a few large joints such as the hip or knee but can also involve the vertebrae and sacroiliac joints (joining the lower spine to the pelvis).
Angina when beginning nifedipine therapy. Oral Dry mouth, gingival hyperplasia. GI Nausea, diarrhea, constipation, flatulence, abdominal cramps, dysgeusia, vomiting, eructation, gastroesophageal reflux, melena. CNS Dizziness, lightheadedness, giddiness, nervousness, sleep disturbances, headache, weakness, depression, migraine, psychoses, hallucinations, disturbances in equilibrium, somnolence, insomnia, abnormal dreams, malaise, anxiety. Dermatologic Rash, dermatitis, urticaria, pruritus, photosensitivity, erythema multiforme, Stevens-Johnson syndrome. Respiratory Dyspnea, cough, wheezing, SOB, respiratory infection, throat, nasal, or chest congestion. Musculoskeletal Muscle cramps or inflammation, joint pain or stiffness, arthritis, ataxia, myoclonic dystonia, hypertonia, asthenia. Hematologic Thrombocytopenia, leukopenia, purpura, anemia. Other Fever, chills, sweating, blurred vision, sexual difficulties, flushing, transient blindness, hyperglycemia, hypokale-mia, allergic...
Zhang Ji (150-219 a.d.) in his classic text On Cold Damage (Shang Han Lun) recommends a decoction of A. annua to treat fevers with sweating and jaundice (Mitchell et al., 1999). He recommends that fruits of Gardenia jasminoides and roots of rhubarb (Rheum palmatum) should be added to the decoction. The Handbook of Prescriptions for Emergency Treatment (Zhouhou Beiji Fang), written in 340 a.d., also recommends the use of Qing Hao for intermittent fevers. The
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