Age and Gender Distribution of Patients with Invasive K kingae Disease

Sixty-one of the 96 (63.5%) patients diagnosed at the SUMC during a 17-year period were males. The age-distribution of these patients shows that only one was younger than 6 months, 78 (81.3%) patients were aged 6-24 months, and overall 94 of 96 (97.9%) patients were younger than 4 years (Figure 15.3). It should be pointed-out that the remaining two cases that included the oldest child in the series (aged lower respiratory tract infection (3)

occult bacteremia i occult bacteremia i dactylitis (1) tenosynovitis (1)*"" abortive skeletal infection (4)

endocarditis (2)

septic arthristis (43)

\ osteomyelitis (5)

* osteomyelitis + septic arthritis (1)

Figure 15.3. Clinical presentation of 96 patients with invasive K. kingae infections diagnosed in southern Israel. Reprinted from Lancet Infectious Diseases, Vol 4, Yagupsky et al., "Kingella Kingae: from medical rarity to an emerging paediatric pathogen," 332-41, 2004, with permission from Elsevier.

66 months) and the only adult were the only patients with endocarditis detected during the entire 17-year period. The calculated annual incidence of invasive K. kingae disease in southern Israel represented between 1/3 and 1/5 of that of H. influenzae type b in the same population prior to the introduction of the conjugate vaccine (Slonim et al., 2003).

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