Mycophenolate mofetil mycophenolic acid

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(Trade name: CellCept) An immunosuppressive drug whose main use is to prevent rejection after organ transplantation. Mycophenolate suppresses the immune system by interfering with DNA synthesis by blocking the formation of purines (building blocks for DNA), particularly in cells such as lymphocytes. Some rheumatologists are using mycophenolate to treat systemic lupus erythe-matosus and as maintenance treatment to keep vasculitis in remission. In patients requiring high doses of corticosteroids to control an autoimmune problem, mycophenolate treatment may allow lower doses of corticosteroids to be used, acting as a steroid-sparing agent.

Side effects Common: GI symptoms such as vomiting, diarrhea, stomach pain, and nausea. Uncommon: Bone marrow suppression, allergic reactions, mild increases in liver enzymes, herpes zoster, and increased risk of infection.

myochrysine See gold injections.

nabumetone (Trade name: Relafen) A nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX-1 and COX-2) enzymes, decreasing the formation of inflammatory mediators such as prostaglandins. NSAIDs are used to treat pain and inflammation resulting from a variety of causes. Common indications are rheumatoid arthritis, osteoarthritis, gout, ankylosing spondylitis, and bursitis. NSAIDs do not affect the progression of arthritis.

Side effects Common: GI symptoms, usually indigestion or heartburn, and fluid retention with ankle edema. Less common: Peptic ulcers with or without complications such as perforation, gastrointestinal obstruction, or bleeding. Risk factors for complicated peptic ulcers caused by NSAIDs are age older than 65 years, previous peptic ulcer or bleeding ulcer, and treatment with a corticosteroid. NSAIDs can increase blood pressure, impair kidney function, and cause abnormal liver function tests (usually mild), rashes, ringing in the ears, and a feeling of lightheadedness. Uncommon: Serious allergy to NSAIDs can result in anaphylaxis with bronchospasm, urticaria, and angioedema.

Nalfon See fenoprofen.

Naprelan See naproxen.

Naprosyn See naproxen.

naproxen (Trade names: Aleve, Anaprox, Naprosyn; controlled-release [slow-release] naproxen: Naprelan) A nonsteroidal antiinflammatory drug (NSAID) that inhibits cyclooxygenase (COX-1 and COX-2) enzymes, decreasing the formation of inflammatory mediators such as prostaglandins. NSAIDs are used to treat pain and inflammation resulting from a variety of causes. Common indications are rheumatoid arthritis, osteoarthritis, gout, ankylosing spondylitis, and bursitis. NSAIDs do not affect the progression of arthritis.

Side effects Common: GI symptoms, usually indigestion or heartburn, and fluid retention with ankle edema. Less common: Peptic ulcers with or without complications such as perforation, gastrointestinal obstruction, or bleeding. Risk factors for complicated peptic ulcers caused by NSAIDs are age older than 65 years, previous peptic ulcer or bleeding ulcer, and treatment with a corticosteroid. NSAIDs can increase blood pressure, impair kidney function, and cause abnormal liver function tests (usually mild), rashes, ringing in the ears, and a feeling of lightheadedness. Uncommon: Serious allergy to NSAIDs can result in anaphylaxis with bronchospasm, urticaria, and angioedema.

Neoral See cyclosporine.

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Responses

  • jyri
    Is mycophenolate prescribed for bursitis?
    3 years ago
  • catriona
    Can mycophenolic acid be used for osteoarthritis?
    2 years ago
  • Rhea
    Is mycophenolate mofetil a nsaid?
    4 months ago

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