Nonsteroidal anti-inflammatory drugs Steroids Topical agents Capsaicin
Methyl salicylate creams Intra-articular injections Glucocorticoids Hyaluronic acid Nonpharmacologic interventions Physical therapy Weight loss Surgical management Arthroplasty
Arthroscopic removal of loose bodies
Correction of anatomic defects (spondylosis, spinal stenosis) Emerging trends
Exogenous growth factors (to stimulate chondrocyte proliferation) Transplantation of healthy chondrocytes, engineered to maximally produce growth factors ticularly because patients tend to minimize activity levels so as to avoid pain. Thus, they run the risk of becoming deconditioned and less capable of sustaining aerobic activity and physical fitness. Pain relief can be brought forth by any of the NSAIDs. Celecoxib might be better tolerated because of its reduced propensity to interfere with gastric and renal functioning (see also Chapter 5, "Pharmacology of Pain," of this book for adverse effects associated with NSAIDs and cyclooxygenase-2 inhibitors). These and other medications to employ in the treatment of osteoarthritis are summarized in Table 8-11.
Rheumatoid arthritis, on the other hand, is an inflammatory process affecting the synovium of articular joints and producing a number of systemic manifestations. Rheumatoid arthritis affects approximately 1%-2% of the population, with about two to three times as many women affected as men. The joints affected by rheumatoid arthritis include the hands, wrists, elbows, ankles,
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Thank you for deciding to learn more about the disorder, Osteoarthritis. Inside these pages, you will learn what it is, who is most at risk for developing it, what causes it, and some treatment plans to help those that do have it feel better. While there is no definitive “cure” for Osteoarthritis, there are ways in which individuals can improve their quality of life and change the discomfort level to one that can be tolerated on a daily basis.