Melatonin Ebooks Catalog

Natural Insomnia Program

Natural Insomnia Program is credited to Christian Goodman, who is a health expert, and he is willing to help those people suffering from insomnia for long. Many people end up suffering from the sleepless night, which ends up affecting their following day schedule. For instance, the author sleepless night has destructed his marriage and also career, but with the help of the program, he has been to overcomes this problem. Through the various studies, it shows that most of the people sleep after 45 minutes, but with the help of the program, this would be reduced to 10 to 15 minutes. The most common solution to relaxing the body is through linguistic audio, which would help the brain to relax and thus sleep effectively. Many people have used the program, and they have ended solving the problem entirely. The program is available either in the video series and e-Book and works within the shortest time possible. Continue reading...

Natural Insomnia Program Summary


4.8 stars out of 17 votes

Contents: Ebook, Video Series
Author: Christian Goodman
Official Website:
Price: $49.00

Access Now

My Natural Insomnia Program Review

Highly Recommended

The writer presents a well detailed summery of the major headings. As a professional in this field, I must say that the points shared in this manual are precise.

All the testing and user reviews show that Natural Insomnia Program is definitely legit and highly recommended.

Cure Insomnia Six Steps To Sleep

The Cure Insomnia for Good with Six Steps to Sleep is a popular sleep program that persons who are facing the difficulty of having a sound sleep and usually have stressful days undertake; to retrain their body for a night of deep and restful sleep. This program uses a proven six steps sleep hygiene method that will naturally reset your sleep-wake cycle. This puts a stop to sleepless nights giving you a wonderful and energetic feeling in the morning and all day. From the book you will discover a lot which includes; how to fall asleep just within minutes of lying on your bed, how to stop your mind from wandering as you lay on the bed about to sleep, how you can stop the feeling of anxiety and restless when you are about to sleep, how to sleep properly when you are sharing the bed with a partner, how you can sleep soundly in a new environment and how you can get a sound sleep for about 7 hours in the night. This product is available for sale in hard copies and also on the site. It comes together with the book and the six steps to sleep program together with a guide for diet and 4 audio brainwave meditations, all of which contribute to relaxing the mind and body. Continue reading...

Cure Insomnia Six Steps To Sleep Summary

Contents: 9 Chapters Ebook, Mp3 Binaural Beats Recordings
Author: Peter Litchfield
Official Website:
Price: $19.00

Natural Night Sleep Hypnosis

The Natural Night Sleep Program is designed so that you will fall asleep easily by simply listening to the recording. As you go to bed, you will: Be guided you to quieten your mind, relax your body and drift in to a deep sleep within 20 minutes of lying in bed every night. With regular listening, you'll fall asleep faster and your sleep cycles will deepen. Enjoy a whole night of deep sleep, and wake up feeling refreshed and energised. You will re-engage your bodys natural sleep and waking rhythms. Unwind and enjoy beautiful ethereal ambient music by award winning ambient Canadian artist Marcom . Hypnosis suggestions are spoken with this enchanting music in the background. Give up struggling through days of being listless and tired due to a poor nights sleep. (Poor sleep also costs you time, money and lost opportunities by preventing you from being fully present each day). By guiding you into a deep nights sleep the recording enables rejuvenation and allows you to enjoy high daytime energy levels and focus you'll be free to create a day of your choice rather than dragging yourself through the day's activities. Enjoy restful sleep throughout the night, so that you can consistently be at your best and feel revitalised and vibrant through your day. Be guided to clear your mind, release the mental chatter, and relax your body completely so you effortlessly drift off to sleep. You will sleep deeper throughout the night. Be confident about falling asleep quickly if you should awaken during the night for any reason. Develop new sleeping habits and beneficial patterns that work for you. through suggestions delivered to your sub-conscious mind even as you fall asleep. Continue reading...

Natural Night Sleep Hypnosis Summary

Contents: EBook, 3 Track Mp3 Recording
Author: Johneal Rouse
Official Website:
Price: $9.95

Sleep Deprivation

Sleep deprivation refers to being deprived of the recommended hours of sleep for healthy adults. Sleep deprivation can dramatically worsen fatigue in people who are hypothyroid. In people who are thyrotoxic, sleep deprivation can contribute to exhaustion, but sleep is difficult anyway because the body is working too hard at night, which interferes with a good night's sleep. In the absence of hypothyroidism or thyrotoxicosis, people who have multiple demands and or jobs that require long hours are often sleep deprived, which can have serious health repercussions. In fact, some research suggests that chronic fatigue as well as fibromyalgia may be directly linked to chronic sleep deprivation. One Canadian study deliberately deprived a group of medical students of non-REM sleep over a period of several nights. Within the next few days, each of the study participants developed symptoms of CFS and or fibromyalgia. There are two phases of sleep rapid eye movement (REM) and non-rapid eye...


Insomnia is when you are aware of poor quality sleep because you cannot fall asleep wake up a lot during the night and cannot fall back asleep (also a sign of depression) wake up too early in the morning or have the sense that your sleep is fitful or unre-freshing. Most causes of insomnia are linked to mental or emotional stress, and it is seen more frequently in people over sixty, women, and people who suffer from depression. Most people have only transient or intermittent bouts of insomnia that resolve once a particularly stressful period has passed. Insomnia can also be linked to medication side effects, caffeine, smoking, or alcohol before bedtime. Chronic insomnia is often linked to depression, but is also seen in people with arthritis (because of nighttime discomfort), kidney disease, heart failure, asthma, sleep apnea, restless legs syndrome (described later), and Parkinson's disease. Insomnia is generally treated through behavioral therapy and lifestyle modification. When you...

Sleep Disorders

Sleep disorders are rather common in the general population and include (1) dyssomnias, (2) parasom-nias, and (3) sleep dysfunction secondary to other neurological, general medical, or psychiatric disorders. Dyssomnias are by far the most common sleep disorders and represent conditions wherein the patient has difficulty either initiating or maintaining sleep some have both syndromes. Both are characterized by chronic irritability, feelings of tiredness, excessive daytime sleepiness, poor concentration, and, in some cases, significant memory impairment. Etiological factors are widely variable and include recent significant stressors, poor sleep hygiene, and disturbances in circadian rhythm. The former is primarily an excessive arousal reaction to stress, which can be treated pharmacologically with arousal modulating agents. Trazodone has long been used to reduce nocturnal arousal and normalize sleep architecture. More recently, Nefazodone has been used similarly and shown to improve...

Adjuvant Arthritis Disrupts Normal Chronobiological Organization

Summary of changes in circadian rhythms of hypothalamic and hypophysial hormones and neurotransmitters, pineal melatonin and plasma proteins during the preclinical (3rd day) phases of Freund's adjuvant arthritis in rats. Melatonin Table 3.3. Summary of changes in circadian rhythms of hypothalamic and hypophysial hormones and neurotransmitters, pineal melatonin and plasma proteins during the acute (18th day) phase of Freund's adjuvant arthritis in rats. Table 3.3. Summary of changes in circadian rhythms of hypothalamic and hypophysial hormones and neurotransmitters, pineal melatonin and plasma proteins during the acute (18th day) phase of Freund's adjuvant arthritis in rats. Melatonin

Effects of Experimental Sleep Loss

Few clinical studies have studied sleep and immunity in persons with primary insomnia. However, sleep deprivation studies, in which healthy participants are required to undergo extended periods of wakefulness, provide some clues. Partial sleep deprivation studies typically involve 4 h of sleep deprivation and as such, are more closely related to sleep loss in insomnia patients. In studies with healthy participants, partial sleep deprivation results in decreased natural killer (NK) cell activity, independent of changes in actual numbers of natural killer cells, which also decrease (Irwin, McClintick, Costlow, Fortner, White, and Gillin 1996). This subset of cells represent an important line of defense against viral infections and in tumor surveillance (Ben-Eliyahu, Shakhar, Page, Stefanski, and Shakhar 2000). Although the implications of decreased NK activity in healthy participants are unclear, some studies show that decreases NK activity in cancer patients is associated with poorer...

Diagnosis of restless legs syndrome and periodic limb movement disorder

Due to the nocturnal worsening of symptoms, RLS has its greatest impact on sleep. Sleep disturbance is the most frequent reason that patients with RLS seek medical help 3 . Patients with RLS may suffer from severely disrupted sleep, which mostly presents as initial insomnia. Polysomnography, although not routinely indicated for the evaluation of RLS, reveals an elevated number of periodic leg movements during sleep (PLMS) in 80-90 of RLS cases 4 . PLMS are a sleep-related phenomenon that manifest with periodic episodes of repetitive, stereotyped leg movements 5,6 . These periodic movements are characterized by the extension of the big toe in combination with flexion of the ankle, knee, and sometimes the hip. Most RLS patients also will demonstrate periodic leg movements during wakefulness (PLMW) during polysomnographic recordings while awake 6 . PLMS are not specific to RLS and may frequently occur in other sleep disorders such as narcolepsy, obstructive sleep apnea syndrome, or REM...

Fibromyalgia and rheumatoid diseases

Chronic medical conditions may also cause significant sleep disturbance and manifest clinically as either EDS or fatigue. Patients with fibromyalgia frequently characterize their sleep as being restless, light, and unrefreshing 63 . These patients often have an alpha-frequency EEG coincident with delta-frequency sleep, or alpha-delta sleep 64 . Alpha activity is characteristic of the EEG pattern seen during quiet wakefulness with the eyes closed and does not typically occur during deep sleep (when delta activity occurs) in normal subjects. This EEG finding has also been reported to occur in rheumatoid arthritis and chronic fatigue syndrome 65,66 . Researchers have found a positive correlation between the frequency of alpha-delta sleep and severity of overnight pain in patients with fibromyalgia, and an inverse correlation between frequency of alpha-delta sleep and subjective sleep depth and or refreshing sleep 67,68 .

Sleep and Cytokines in Rheumatoid Arthritis

The prevalence of sleep disturbance can be quite high in autoimmune disorders for example, 50 of multiple sclerosis patients report clinically relevant sleep complaints (Fleming and Pollak 2005) as do 61 of systemic lupus patients (Tench, McCurdie, White, and D'Cruz 2000). Perhaps the highest prevalence is in rheumatoid arthritis (RA) patients, between 50 and 75 of patients complain of difficulties initiating or maintaining sleep (Drewes 1999). Fatigue is a debilitating symptom in each of these conditions, and studies show that poor sleep is significant predictor of fatigue, often more so than other disease-specific variables (Nicassio, Moxham, Schuman, and Gevirtz 2002). Although the underlying causes of sleep difficulties can include medication effects as well as chronic pain, studies with RA patients are indicating that inflammatory cytokines might be important promoters of sleep dysregulation. RA patients report frequent difficulties with sleep polysomnography studies show that RA...

Cytokines Role in the Regulation of Sleep

Although sleep deprivation studies and insomnia studies both indicate that inflammatory cytokines are elevated subsequent to sleep loss, cytokines themselves appear to impact sleep. Animal studies indicate that administration of inflammatory cytokines have varying effects on sleep, depending on the nature, timing, and dose of cytokine administered. IL-6 has been described as a sleep modulator and its administration produces sleep fragmentation in rats (Hogan et al. 2003). IL-1 and TNF produce increases in nonrapid eye movement (NREM) sleep in mice, rats, and rabbits. However, the effects of proinflammatory cytokines on sleep continuity and fragmentation in humans is far less clear, partially because cytokine administration studies are rare. In healthy subjects, IL-6 and interferon-gamma (IFN- ) administration decreases amounts of SWS in the first half of the night and substantially increases SWS in the second half of the night (Spath-Schwalbe et al. 1998 Spath-Schwalbe et al. 2000)....

Mlt Effects

Immunodeficiency states which may follow acute stress, viral diseases, or drug treatment (51,53,54,56,59-61). This finding has been then confirmed and extended either in mice or in humans to a variety of immune parameters (15,16,22,26,49,64,67,68). On this line, a very significant biological effect of MLT is the protection of mice against encephalitis viruses and lethal bacterial (8,9,13). In general, the immunoenhancing action of MLT seems restricted to T-dependent antigens and to be most pronounced in immunodepressed situations. For example, MLT may completely counteract thymus involution and the immunological depression induced by stress events or glucocorti-coid treatment (54). MLT is active only when injected in the afternoon or in the evening, i.e. with a schedule consonant with its physiological rhythm (59,60). In addition, MLT is most active on antigen or cytokine activated immunocompetent cells (59,60). Consistent with these requirements, a recent report shows that MLT may...

The Cascade of Inflammatory Signaling

Demonstrating the role played by adipokines in this disorder. Even restricted sleep can induce insulin resistance and progression toward type 2 diabetes. Alterations in leptin, ghrelin, growth hormone, and body mass index have been found with sleep deprivation (approx. 4-5 h per night).

Genetic Aspects Of Narcolepsy

Narcolepsy Chromosome

Only 25 to 31 of monozygotic twins are concordant for narcolepsy.29 In one case, low and high CSF hypocretin-1 levels were reported in monozygotic twins with and without narcolepsy, respectively.30 Symptomatic concordance in monozygotic twins has been reported in the face of HLA-DQB1*0602 positivity with normal hypocretin levels31 or in the context of HLA negativity.29 This suggests that some non-HLA, non-hypocretin-mediated cases of narcolepsy may have a yet undetermined genetic basis. As discordant twins can develop narcolepsy later in life in association with environmental triggers such as emotional stress or chronic sleep deprivation,32 additional, non-genetic factors are likely to be associated with the onset of the disease. The finding that approximately 25 of familial narcoleptic cases are negative for DQB1*060225,51 points towards the existence of highly penetrant non-HLA narcolepsy genes. Systematic genome screening in extended narcoleptic families has revealed a significant...

Respiratory Cardiovascular and Motor Changes During Sleep in the Elderly

The significance of respiratory dysfunction associated with sleep in the otherwise normal elderly is not well understood (56). Several factors appear to be involved, including aging-related alterations in neural and chemical regulation of respiration (Chapter 17). Abnormal rhythm of the heartbeat cardiac arrhythmias (Chapter 20) and pulmonary hypertension are common during apneic periods (57). Apnea, arrhythmia, and hypertension are usually most frequent during REM sleep they have been related to an increased release of norepinephrine from sympathetic stimulation, with mental disorders such as depression, or with the use of some neuro-tropic medications (Chapter 22).

Treatment and Outcome

No specific treatment is available for Gulf War syndrome. Treatment is symptomatic and similar to that prescribed for fibromyalgia. Low doses of antidepressants are used to improve sleep and decrease fatigue. Clinicians often prescribe cognitive behavioral therapy and exercise. These treatments have been found to be effective in fibromyalgia. A large, randomized study of the efficacy of these interventions in Gulf War syndrome is underway.

Asthenia Crurum Dolorosa Pain and the Opiate System in RLS

An increase in pain sensitivity i.e., static mechanical hyperalgesia, was shown in one study in RLS patients (180). Interestingly, this increased pain sensitivity was significantly reduced after long-term (one year) but not short-term levodopa treatment. However, pain sensitivity is also associated with poor sleep and depression (181) and slow wave sleep deprivation (182), all factors present to a certain degree in RLS. The above-mentioned study (see Section ''Thalamus'') with 11C diprenorphine PET (126) found no difference of opioid binding between RLS subjects and controls, but within the group of RLS subjects opioid receptor binding correlated with RLS severity and questionnaire-based pain scores. The most convincing evidence supporting involvement of the opiate system, of course, is based on the effectiveness of opioidergic treatment in RLS (183-185), (Chapter 27). Challenges of the opiate system in RLS patients (186) showed that administration of naloxone to opiate-treated...

Tylenol See acetaminophen

Side effects Common Dizziness, insomnia or drowsiness, dry mouth, and GI side effects such as nausea and diarrhea. Uncommon Tremor, confusion, rash, sexual dysfunction, sedation, allergy, anticholinergic side effects such as blurred vision, constipation, and slowness or difficulty passing urine. Zolpidem (Trade name Ambien) A hypnotic (sleeping pill) used to improve sleep in conditions such as fibromyalgia. Zolpidem binds to the same receptors in the brain that drugs such as diazepam (trade name Valium) and other benzodiazepines bind to causing sleepiness.

Choose Your Foods Wisely

For sleep problems try 5-HTP tryptophan (an amino acid), melatonin, calcium, magnesium, valerian in caps, extract or tea, Bragg vinegar drink, sleepytime herbal tea. For arthritis, osteoarthritis, pain stiffness, try aloe juice or gel, glucosamine, chondroitin & MSM combo (caps & liquid), helps heal & regenerate. Also capsaicin & dmso lotion helps.

Nuclear Factorkappa B and Activator Protein1

Melatonin Inhibition of NF-kB and AP-1 activity, and especially NF-kB activity, has been demonstrated in vitro by a number of different antioxidants. Table 5.1 lists some of these in order of decreasing potency. As the table indicates, the ability of antioxidants to affect NF-kB activity varies greatly. Whereas moderately lipophilic (fat-soluble) antioxidants such as melatonin more strongly affect NF-kB activity, water-soluble antioxidants like vitamin C and strongly lipophilic antioxidants like vitamin E are substantially weaker.33,72-74, a In spite of their activity in vitro, it is unlikely that these antioxidants strongly inhibit NF-kB activity in vivo, at least when used alone. The concentrations at which an-tioxidants are active in vitro are greater than those normally present in the body, even after supplementation. For example, the plasma concentration of melatonin in humans after an extremely large (100-milligram) dose is only about 440 nM.77 This is 23-fold lower than the...

Janet L Cummings

Norepinephrine Also called noradrenaline a neurotransmit-ter that interacts with epinephrine to affect autonomic activity and mood. perturbations Hypothesized structures throughout the body believed by proponents of thought field therapy to contain the energy that creates psychological disturbances. Piper methysticum Also called kava or kava kava an herbal compound marketed over-the-counter for the treatment of anxiety and insomnia. platelets Cell-like particles in the blood, smaller than red or white blood cells, which clump together and promote clotting. associated with depression. serotonin syndrome A syndrome caused by high levels of serotonin and associated with agitation, restlessness, insomnia, tremor, nausea, vomiting, rapid heart rate, and seizures. sertraline (Zoloft) A selective serotonin reuptake inhibitor. SSRIs (See selective serotonin reuptake inhibitors). St. John's wort (See Hypericum perforatum). thought field therapy An alternative to psychotherapy in which the...

Main Cues

EDS is a challenging symptom because of a significant overlap with features of fatigue and the difficulty patients and physicians have in differentiating between the two symptoms. Sleepiness is the tendency to fall asleep, whereas fatigue involves a task context with musculoskeletal and or neurasthenic qualities. For instance, one author has described fatigue as a drive for rest, and daytime sleepiness as a drive for sleep (6). Sleepiness may occur more often during passive conditions, such as watching television or sitting as a passenger in a car but in its most severe form, sleepiness can intrude into active conditions, such as talking to someone or driving a car. Insomnia Insomnia is a repeated difficulty with sleep initiation, duration, consolidation, or quality that occurs despite adequate time and opportunity for sleep and results in some form of daytime impairment (20). Collectively, insomnia encompasses adequate sleep opportunity, a persistent sleep difficulty, and associated...

Clinical History

Obtaining a detailed clinical history is especially important when diagnosing a sleep disturbance because routine physical examination is often not revealing during the waking hours. From the history, age of onset, duration and progression of the sleep complaint, and the general classification of the type of sleep disturbance is usually obtained. The International Classification of Sleep Disorders categorizes sleep disturbances as (1) dyssomnias or disorders that result in insomnia or excessive sleepiness (2) parasomnias or disorders of arousal, partial arousal, or sleep stage transition and (3) sleep disorders associated with medical or psychiatric disorders. The dyssomnias include the intrinsic sleep disorders arising from bodily malfunctions such as psychophysiological insomnia, obstructive and central sleep apnea, restless legs syndrome (RLS), and periodic limb movement disorder (PLMD). Examples of parasomnias include sleep walking, sleep terrors, sleep talking, nightmares, REM...

Rheumatoid arthritis

This is characterized by early morning stiffness and pain, although the precise cause of this remains uncertain. Sleep is unrefreshing and there is a reduced duration of stages 3 and 4 NREM sleep and REM sleep. REM sleep deprivation also lowers the pain threshold. Polysomnography shows alpha intrusion into stages 3 and 4 NREM sleep as well as a reduced sleep efficiency.


The main theories regarding the ability of massage to reduce pain include gate theory, serotonin, and restorative sleep (91). According to gate theory (92), because pressure receptors are longer and more myelinated than pain fibers, pressure signals from massage are transmitted faster, closing the gate to pain signals. The serotonin hypothesis maintains that massage appears to increase levels of serotonin, a neurotransmitter that modulates the pain control system (93). The restorative sleep hypothesis holds that because substance P, a neuro-transmitter associated with pain, is released in the absence of deep sleep, the

Theories Of Aging

This theory suggests that aging is caused by endocrine dysfunction, which is common in elderly people. Changes in hormonal secretion, loss of receptor sensitivity to stimulatory or inhibitory stimuli, anatomic changes of endocrine glands, and altered transport of hormones occur with aging.27 Many hormones decrease with aging. Studies have shown that melatonin secreted from the pineal gland (responsible for regulation of circadian rhythms) decreases with age. Specifically, increasing age is directly proportional to decreasing levels of plasma melatonin and delayed melatonin elevation.28 Growth hormone decreases at approximately 14 per decade. After age 60, growth hormone is decreased by approximately 50 -70 compared with levels in the third and fourth decade of life.29 Steroid hormones, such as estrogen and testosterone, also decrease with age.30 Interestingly, estrogen has been shown to up-regulate telomerase activity.31 Animal studies have also demonstrated that testosterone may...


Tens Unit Placement Neck Pain

Most patients with FM complain of fatigue (see Reference 33, Chapter 55), and many have poor-quality sleep (see Reference 33, Chapter 56). The relation between FM and sleep disturbance is not as clear as once thought.1 Improvement in FM symptoms with pharmacological treatment does not necessarily correlate with an improvement in sleep.6 FM patients also have a higher incidence of migraine and tension headaches than the general population1 (see Reference 33, Chapter 63). Approximately 84 of people with FM complain of numbness or tingling somewhere in the body.7 Echocardiography evidence of mitral valve prolapse is seen in up to 75 of FM patients.8 Patients with FM have a higher incidence of depression, and controversy remains as to whether FM symptoms are a manifestation of a psychosomatic syndrome, or, conversely, depression results from chronic pain (see Reference 33, Chapters 32 and 61). Medication. Amitriptyline (Elavil and others) and cyclobenzaprine (Flexeril) have been studied...

Eduquer Un Purich

Benes L, Claustrat B, Horriere F et al. Transmucosal, oral controlled-release, and transdermal drug administration in human subjects a crossover study with melatonin. J Pharm Sa 1997 86 1115-1119. Fourtillan J B, Brisson A M, Gobin P et al. Bioavailability of melatonin in humans after day-time administration of D7 melatonin. Biopharm Drug Disp 2000 21 15-22.

Sirens Sleep Solution

Sirens Sleep Solution

Discover How To Sleep In Peace And Harmony In A World Full Of Uncertainty And Dramatically Improve Your Quality Of Life Today! Finally You Can Fully Equip Yourself With These “Must Have” Tools For Achieving Peace And Calmness And Live A Life Of Comfort That You Deserve!

Get My Free Ebook