Cortisol Prevents the Development of Inflammation by Stabilizing Lysosomes and by Other Effects Cortisol has the

Cortisol stabilizes the lysosomal membranes. This is one of its most important anti-inflammatory effects, because it is much more difficult than normal for the membranes of the intracellular lysosomes to rupture. Therefore, most of the proteolytic enzymes that are released by damaged cells to cause inflammation, which are mainly stored in the lysosomes, are released in greatly decreased quantity. 2. Cortisol decreases the permeability of the capillaries, probably as a secondary effect of the...