Cure Arthritis Naturally

Cure Arthritis Naturally

Get Instant Access

Andrade F, Roy S, Nicholson D, Thornberry N, Rosen A, Casciola-Rosen L (1998) Granzyme B directly and efficiently cleaves several downstream caspase substrates: Implications for CTL-induced apoptosis. Immunity 8:451-460 Andrade F, Casciola-Rosen L, Rosen A (2001) Novel covalent UlRNA-protein complexes are generated in cells by ultraviolet B (UVB) irradiation: implications for autoimmunity. Arthritis Rheum 44:S304

Bach JF, Koutouzov S (1997) Immunology. New clues to systemic lupus. Lancet 350(Suppl 3):11 Berthou C, Michel L, Soulie A, Jean-Louis F, Flageul B, Dubertret L, Sigaux F, Zhang Y, Sasportes M (1997) Acquisition of granzyme B and Fas ligand proteins by human keratinocytes contributes to epidermal cell defense. J Immunol 159:5293-5300 Botto M, Dell'Agnola C, Bygrave AE, Thompson EM, Cook HT, Petry F, Loos M, Pandolfi PP,Wal-port MJ (1998) Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet 19:56-59 Buyon JP (1996) Neonatal lupus: bedside to bench and back. Scand J Rheumatol 25:271-276 Carroll MC (1998) The lupus paradox. Nat Genet 19:3-4

Casciola-Rosen LA, Rosen A (1997) Ultraviolet light-induced keratinocyte apoptosis: a potential mechanism for the induction of skin lesions and autoantibody production in LE. Lupus 6:175-180

Casciola-Rosen LA, Anhalt G, Rosen A (1994) Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 179:1317-1330 Casciola-Rosen LA, Anhalt GJ, Rosen A (1995) DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis. J Exp Med 182:1625-1634 Casciola-Rosen LA, Rosen A, Petri M, Schlissel M (1996) Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus. Proc Natl Acad Sci USA 93:1624-1629 Casciola-Rosen LA, Andrade F, Ulanet D, Wong WB, Rosen A (1999) Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity. J Exp Med 190:815-825

Chung JH, Kwon OS, Eun HC,Youn JI, Song YW, Kim JG, Cho KH (1998) Apoptosis in the patho-

genesis of cutaneous lupus erythematosus. Am J Dermatopathol 20:233-241 Cocca BA, Seal SN, D'Agnillo P, Mueller YM, Katsikis PD, Rauch J, Weigert M, Radic MZ (2001) Structural basis for autoantibody recognition of phosphatidylserine-beta 2 glycoprotein I and apoptotic cells. Proc Natl Acad Sci U S A 98:13826-13831 Diamond B, Katz JB, Paul E, Aranow C, Lustgarten D, Scharff MD (1992) The role of somatic mutation in the pathogenic anti-DNA response. Ann Rev Immunol 10:731-757

Fadok VA,Voelker DR, Campbell PA, Cohen JJ, Bratton DL, Henson PM (1992) Exposure of phos-phatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 148:2207-2216 Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM (1998) Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-ß, PGE2, and PAF. J Clin Invest 101:890-898

Fadok VA, Bratton DL, Henson PM (2001) Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences. J Clin Invest 108:957-962 Furukawa F, Kashihara-Sawami M, Lyons MB, Norris DA (1990) Binding of antibodies to the extractable nuclear antigens of SS-A/Ro and SS-B/La is induced on the surface of human ker-atinocytes by ultraviolet light (UVL): implications for the pathogenesis of photosensitive cutaneous lupus. J Invest Dermatol 94:77-85 Gallucci S, Lolkema M, Matzinger P (1999) Natural adjuvants: endogenous activators of dendritic cells. Nat Med 5:1249-1255 Gershov D, Kim S, Brot N, Elkon KB (2000) C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiin-flammatory innate immune response: implications for systemic autoimmunity. J Exp Med 192:1353-1364

Golan TD, Elkon KB, Gharavi AE, Krueger JG (1992) Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus patients after ultraviolet B/ultraviolet A irradiation. J Clin Invest 90:1067-1076 Hengartner MO (2000) The biochemistry of apoptosis. Nature 407:770-776 Henson PM, Bratton DL, Fadok VA (2001) Apoptotic cell removal. Curr Biol 11:R795-805 Hoffmann PR, deCathelineau AM, Ogden CA, Leverrier Y, Bratton DL, Daleke DL, Ridley AJ, Fadok VA, Henson PM (2001) Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells. J Cell Biol 155:649-659 Huynh ML, Fadok VA, Henson PM (2002) Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. J Clin Invest 109:41-50

Lee LA, Frank MB, McCubbin VR, Reichlin M (1994a) Autoantibodies of neonatal lupus erythematosus. J Invest Dermatol 102:963-966 Lee LA, Roberts CM, Frank MB, McCubbin VR, Reichlin M (1994b) The autoantibody response to Ro/SSA in cutaneous lupus erythematosus. Arch Dermatol 130:1262-1268 LeFeber WP, Norris DA, Ryan SR, Huff JC, Lee LA, Kubo M, Boyce ST, Kotzin BL, Weston WL (1984) Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytes. J Clin Invest 74:1545-1551 Lu Q, Lemke G (2001) Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 293:306-311 Manfredi AA, Rovere P, Galati G, Heltai S, Bozzolo E, Soldini L, Davoust J, Balestrieri G, Tincani A, Sabbadini MG (1998) Apoptotic cell clearance in systemic lupus erythematosus. 1. Opsonization by antiphospholipid antibodies. Arthritis Rheum 41:205-214 Miranda ME, Tseng CE, Rashbaum W, Ochs RL, Casiano CA, Di Donato F, Chan EK, Buyon JP (1998) Accessibility of SSA/Ro and SSB/La antigens to maternal autoantibodies in apoptotic human fetal cardiac myocytes. J Immunol 161:5061-5069 Miranda-Carus ME, Askanase AD, Clancy RM, Di Donato F, Chou TM, Libera MR, Chan EK, Buyon JP (2000) Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-alpha by macrophages. J Immunol 165: 5345-5351

Natali PG, Tan EM (1973) Experimental skin lesions in mice resembling systemic lupus erythe-

matosus. Arthritis Rheum 16:579-589 Odin JA, Huebert RC, Casciola-Rosen L, LaRusso NF, Rosen A (2001) Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis. J Clin Invest 108:223-232

Orteu CH, Sontheimer RD, Dutz JP (2001) The pathophysiology of photosensitivity in lupus erythematosus. Photodermatol Photoimmunol Photomed 17:95-113 Pablos JL, Santiago B, Galindo M, Carreira PE, Ballestin C, Gomez-Reino JJ (1999) Keratinocyte apoptosis andp53 expression in cutaneous lupus and dermatomyositis. J Pathol 188:63-68 Price BE, Rauch J, Shia MA, Walsh MT, Lieberthal W, Gilligan HM, O'Laughlin T, Koh JS, Levine JS (1996) Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a ß2-glycoprotein I-dependent manner. J Immunol 157:2201-2208 Provost TT, Reichlin M (1988) Immunopathologic studies of cutaneous lupus erythematosus. J Clin Invest 8:223-232

Radic MZ, Weigert M (1994) Genetic and structural evidence for antigen selection of anti-DNA

antibodies. Ann Rev Immunol 12:487-520 Rosen A, Casciola-Rosen L (1999) Autoantigens as substrates for apoptotic proteases: Implications for the pathogenesis of systemic autoimmune disease. Cell Death Differ 6:6-12 Sauter B, Albert ML, Francisco L, Larsson M, Somersan S, Bhardwaj N (2000) Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med 191:423-434 Savill J, Fadok V (2000) Corpse clearance defines the meaning of cell death. Nature 407:784-788 Scott RS, McMahon EJ, Pop SM, Reap EA, Caricchio R, Cohen PL, Earp HS, Matsushima GK (2001) Phagocytosis and clearance of apoptotic cells is mediated by MER. Nature 411:207-211

Seery JP, Carroll JM, Cattell V,Watt FM (1997) Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis. J Exp Med 186:1451-1459 Simmons-O'Brien E, Chen S,Watson R,Antoni C, Petri M, Hochberg M, Stevens MB, Provost TT (1995) One hundred anti-Ro (SS-A) antibody positive patients: a 10-year follow-up. Medicine (Baltimore) 74:109-130

Somersan S, Bhardwaj N (2001) Tethering and tickling: a new role for the phosphatidylserine receptor. J Cell Biol 155:501-504 Sontheimer RD (1989) Subacute cutaneous lupus erythematosus: a decade's perspective. Med

Clin North Am 73:1073-1090 Taylor PR, Carugati A, Fadok VA, Cook HT, Andrews M, Carroll MC, Savill JS, Henson PM, Botto M, Walport MJ (2000) A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo. J Exp Med 192:359-366 Thornberry NA, Lazebnik Y (1998) Caspases: enemies within. Science 281:1312-1316 Tran HB, Ohlsson M, Beroukas D, Hiscock J, Bradley J, Buyon JP, Gordon TP (2002) Subcellular redistribution of la/SSB autoantigen during physiologic apoptosis in the fetal mouse heart and conduction system: a clue to the pathogenesis of congenital heart block. Arthritis Rheum 46:202-208

Voll RE, Herrmann M, Roth EA, Stach C, Kalden JR, Girkontaite I (1997) Immunosuppressive effects of apoptotic cells. Nature 390:350-351 Young AR (1987) The sunburn cell. Photoderm 4:127-134


Was this article helpful?

0 0
How To Bolster Your Immune System

How To Bolster Your Immune System

All Natural Immune Boosters Proven To Fight Infection, Disease And More. Discover A Natural, Safe Effective Way To Boost Your Immune System Using Ingredients From Your Kitchen Cupboard. The only common sense, no holds barred guide to hit the market today no gimmicks, no pills, just old fashioned common sense remedies to cure colds, influenza, viral infections and more.

Get My Free Audio Book

Post a comment