Contents

Preface v

Series Editor vii

Volume Editors ix

List of Contributors xi

I The Skin and the Immune System

The Skin as an Immunologic Organ 3

Giampiero Girolomoni, Gianpaolo Tessari, Jan D. Bos

T Cells and Dendritic Cells in Immuno-Mediated Skin Pathology 11

Karin Loser, Jenny Apelt, Stefan Beissert

D6 as a Decoy and Scavenger Receptor for Inflammatory CC Chemokines in the Skin 23

Massimo Locati, Yeny Martinez de la Torre, Emanuela Galliera, Raffaella Bonecchi, Gianluca Vago, Annunciata Vecchi, Alberto Mantovani

Autoantibodies and Skin Involvement in Systemic Autoimmune Diseases 29

Ilaria Cavazzana, Angela Tincani, Pierfranco Riboldi, Pier Luigi Meroni

II Skin Involvement in Systemic Autoimmune Diseases

Photosensitivity in Lupus Erythematosus 39

Percy Lehmann

Cutaneous Manifestations of Lupus Erythematosus 49

Annegret Kuhn

Subacute Cutaneous Lupus Erythematosus : A Quarter Century's Perspective 65

Richard D. Sontheimer

Differential Diagnosis of LE-specific Skin Lesions 87

Riccardo Rondinone, Stefania Bano, Luca Iaccarino, Andrea Doria

Dermatologic aspects of Antiphospholipid Antibody Syndrome 103

Camille Frances, Jean-Charles Piette, Ronald A. Asherson

The Skin in Systemic Scleroderma 119

Thorsten M. Olski, Nicolas Hunzelmann, Thomas Krieg

Dermatomyositis 135

Marinos C. Dalakas

Contents

Mucocutaneous Manifestations of Sjogren's Syndrome 147

Stefano Bombardiert, Chiara Baldini

Rheumatoid Arthritis and the Skin 161

Piercarlo Sarzi-Puttini, Fabiola Atzeni, Mario Carrabba

Behcet's Syndrome 185

M. Cem Mat, Cuyan Demirkesen, Melike Melikoglu, Hasan Yazici

Outcome Measure in Cutaneous Autoimmune Disease: Dermatomyositis and Lupus Erythematosus 207 Joerg Albrecht, Victoria P. Werth

Capillaroscopy: Which is Its Role in the Diagnosis of Connective Tissue Diseases? 221

Maurizio Cutolo, Carmen Pizzorni, Maria Elena Secchi, Alessandro Calvia, Alberto Sulli, Marco Matucci Cerinic

III Skin Manifestations in Vasculitides

Cutaneous Small Vessel Vasculitis including Urticarial Vasculitis 235

Manisha J. Patel, Joseph L. Jorizzo

Henoch-Schonlein Purpura 249

Jean-Claude Davin

Mixed Cryoglobulinemia 261

Clodoveo Ferri, Maria Teresa Mascia

Skin Involvement in Small, Medium-sized Vessel and Granulomatous Vasculitides 275

Christian Pagnoux, Camille France's, Marie-Sylvie Doutre, Loi'c Guillevin

Kawasaki Disease 295

Francesco Zulian, Tomisaku Kawasaki

IV New Insight in the Treatment of Skin Manifestations in Systemic Autoimmune Diseases

Skin Targets for New Biological Agents in Systemic Autoimmune Diseases 313

Thomas A. Luger, Markus Boihm

New Trends in Topical and Systemic Immunosuppressive Treatment 325

Matthias Schneider, Rebecca Fischer-Betz, Kristina Gensch, Christof Iking-Konert, Annegret Kuhn

Subject Index

PART I:

The Skin and the Immune System

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Handbook of Systemic Autoimmune Diseases, Volume 5 The Skin in Systemic Autoimmune Diseases

Piercarlo Sarzi-Puttini, Andrea Doria, Giampiero Girolomoni and Annegret Kuhn, editors

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