Table 15.4.1 Incidence ofAdjuvant-lnduced Arthritis in Various Rat Strains
Rat strains RT1 haplotype Incidence"
Buffalo (Buf) b 50%b
Brown Norway (BN) n 100%b
MAXX n 100%
Dark Agouti (DA) av1 100%
Wistar King Aptekman k 75% (WKA)
Fisher (F344) lv1 20%
aIncidence in rats weighing 150 to 300 g.
Strains Buffalo and Brown Norway exhibit sex differences in AA susceptibility. In Buffalo, males are resistant and incidence is reported for females; in Brown Norway, females are resistant and incidence is reported for males.
Adjuvant Arthritis in the Rat
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