Info

tion in lymphocytes. J. Immunol. 139:31993206.

Sellins, K.S. and Cohen, J.J. 1991. Hyperthermia induces apoptosis in thymocytes. Radiat. Res. 126:88-95.

Simon, H.U., Yousefi, S., Dibbert, B., Levi-Schaffer, F., and Blaser, K. 1997. Anti-apoptotic signals of granulocyte-macrophage colony-stimulating factor are transduced via Jak2 tyrosine kinase in eosinophils. Eur. J. Immunol. 27:3536-3539.

Smith, C.A., Williams, G.T., Kingston, R., Jenkin-son, E.J., and Owen, J.J. 1989. Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature 337:181-184.

Strasser, A., Harris, A.W., Huang, D.C., Krammer, P.H., and Cory, S. 1995. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apop-tosis. Embo. J. 14:6136-6147.

Surh, C.D. and Sprent, J. 1994. T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372:100-103.

Telford, W.G., King, L.E., and Fraker, P.J. 1994. Rapid quantitation of apoptosis in pure and heterogeneous cell populations using flow cytometry. J. Immunol. Methods 172:1-16.

Wang, C.Y., Mayo, M.W., Korneluk, R.G., Goeddel, D.V., and Baldwin, A.S. Jr. 1998. NF-kB an-tiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281:1680-1683.

Zheng, L., Fisher, G., Miller, R.E., Peschon, J., Lynch, D.H., and Lenardo, M.J. 1995. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature 377:348-351.

Contributed by Jagan Muppidi, Melissa

Porter, and Richard M. Siegel National Institute of Arthritis and

Musculoskeletal and Skin Diseases Bethesda, Maryland

Measurement of Apoptosis and Other Forms of Cell Death

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