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Ledbetter, J.A. and Herzenberg, L.A. 1979. Xeno-genic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47:6390.

McCormack, J.M., Sun, D., and Walder, W.S. 1991. A subset of mouse splenic macrophages can constitutively present alloantigen directly to CD8+ T cells. J. Immunol. 147:421-427.

McGarry, M.P. and Stewart, C.C. 1991. Murine eos-inophil granulocytes bind the murine macro-phage-monocyte specific monoclonal antibody F4/80. J. Leukocyte Biol. 50:471-478.

Ralph, P., Ho, M.K., Litcofsky, P.B., and Springer, T. A. 1983. Expression and induction in vitro of macrophage differentiation antigens on murine cell lines. J. Immunol. 130:108-114.

Riedy, M.C., Muirhead, K.A., Jenson, C.P., and Stewart, C.C. 1991. Use of a photolabeling technique to identify nonviable cells in fixed homologous or heterologous cell populations. Cytometry. 12:133-139.

Springer, T.A. 1981. Murine macrophage differentiation antigens identified by monoclonal antibodies. In Heterogeneity of Mononuclear Phagocytes (O. Foster and M. Landy, eds.) p. 37. Academic Press, New York.

Stewart, C.C. 1989. Multiparameter flow cytometry for clinical applications. In 1063 New Technologies in Cytometry pp. 150-160. SPIE (Society of Photo-Optical Instrumentation Engineers).

Stewart, C.C., Riedy, M.C., and Stewart, S.J. 1994. Introduction: The proliferation and differentia tion of macrophages. In Macrophage Biology (B.S. Zwilling and T.F. Eisenstein, eds.) pp. 3-27. Marcel Dekker, New York.

Walker, W.S. 1987. Origins of macrophage diversity: Functional and phenotypic analysis of cloned populations of mouse splenic macrophages. Cell. Immunol. 107:417-432.

Walker, W.S. 1989. Differential antigen presentation by cloned populations of mouse splenic macrophages. J. Immunol. 143:2142-2145.

Key References

Stewart, C.C. 1989. See above.

Supplies information necessary to perform three-

color flow cytometric analysis and explains compensation rules.

Stewart, C.C., Riedy, M.C., and Stewart, S.J. 1994. See above.

The book's introduction provides a succinct overview of the macrophage.

Contributed by Mary C. Riedy National Institute of Arthritis and

Musculoskeletal and Skin Diseases Bethesda, Maryland

Carleton C. Stewart Roswell Park Cancer Institute Buffalo, New York

Characterization of Murine Macrophages

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Arthritis Joint Pain

Arthritis Joint Pain

Arthritis is a general term which is commonly associated with a number of painful conditions affecting the joints and bones. The term arthritis literally translates to joint inflammation.

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