1. Hold the mouse (or rat) in a position that allows examination of the paws.
2. Place constant tension-calipers on the ankle (medial/lateral) and determine thickness a minimum of two times to ensure accuracy.
Constant-tension calipers offer the advantage of speed but can yield falsely low values for inflamed joints if the tension is too great.
3. Repeat procedure to measure the tarsal thickness (dorsal/ventral) of the same paw.
4. Repeat steps 2 and 3 for each paw.
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Thank you for deciding to learn more about the disorder, Osteoarthritis. Inside these pages, you will learn what it is, who is most at risk for developing it, what causes it, and some treatment plans to help those that do have it feel better. While there is no definitive “cure” for Osteoarthritis, there are ways in which individuals can improve their quality of life and change the discomfort level to one that can be tolerated on a daily basis.