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Contributed by John J. O'Shea National Institute of Arthritis and

Musculoskeletal and Skin Diseases Bethesda, Maryland

James A. Johnston DNAX

Palo Alto, California John Kehrl

National Institute of Allergy and

Infectious Diseases Bethesda, Maryland

Gary Koretzky

University of Iowa College of Medicine Iowa City, Iowa

Lawrence E. Samelson

National Institute of Child Health and

Human Development Bethesda, Maryland

Key Molecules Involved in Receptor-Mediated Lymphocyte Activation

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Arthritis Joint Pain

Arthritis is a general term which is commonly associated with a number of painful conditions affecting the joints and bones. The term arthritis literally translates to joint inflammation.

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