Many chemokines have been shown to be present in numerous inflammatory and noninflammatory disease states, including sepsis, atherosclerosis, arthritis, cystic fibrosis and asthma. In many of the inflamed lesions the presence of chemokines is highly correlated with the level of leukocyte infiltration within
Table 2 In vitro effects of a and ß chemokine family members
Biological effects on various target cells a Chemokines IL-8, GROa, GROß, GRO-y, NAP-2
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