Further reading

Dyer MJS, Hale G, Hayhoe FGJ and Waldmann H (1989) Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype. Blood 73: 1431-1439. Friend PJ, Rebello P, Oliveira D et al (1995) Successful treatment of renal allograft rejection with a humanized antilymphocyte monoclonal antibody. Transplantation Proceedings 27: 869-870. Hale G and Phillips JM (1995) Clinical trials with CAM-PATH-1 and other monoclonal antibodies. Biochemical Society Transactions 23: 1057-1063. Hale G and Waldmann H (1994) CAMPATH-1 monoclonal antibodies in bone marrow transplantation. Hematotherapy 3: 15-31.

Hale G, Dyer MJS, Clark MR et al (1988) Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1 H. Lancet ii: 1394-1399.

Hale G, Rye PD, Warford A, Lauder 1 and Brito-Babapulle A (1993) The GPI-anchored lymphocyte antigen CDw52 is associated with the epididymal maturation of human spermatozoa. Journal of Reproductive Immunology 23: 189-205.

Isaacs JD, Watts RA, Hazleman BL et al (1992) Humanised monoclonal antibody therapy for rheumatoid arthritis. Lancet 340: 748-752.

Kirchhoff C and Hale G (1996) Cell to cell transfer of gly-cosylphosphatidylinositol-anchored membrane proteins during sperm maturation. Molecular Human Reproduction 2: 177-184.

Kirchhoff C, Krull N, Pera 1 and Ivell R (1992) A major mRNA of the human epididymal principal cells, HE5, encodes the leucocyte differentiation CDw52 antigen peptide backbone. Molecular Reproduction and Development 34: 11-15.

Lockwood CM, Thiru S, Isaacs JD, Hale G and Waldmann H (1993) Humanised monoclonal antibody treatment for intractable systemic vasculitis. Lancet 341: 1620-1622.

Mehta J, Powles R, Treleaven J et al (1997) Autologous transplantation with CD52 monoclonal antibody-purged marrow for acure lymphoblastic leukemia: long-term follow-up. Leukemia Lymphoma 25: 479-486.

Moreau T, Thorpe J, Miller D et al (1994) Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depiction in multiple sclerosis. Lancet 344: 298-301.

Osterborg A, Dyer MJ, Bunjes D et al (1997) Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1 H Treatment in Chronic Lymphocytic Leukemia. Journal of Clinical Oncology 15: 1567-1574.

Osterborg A, Fassas AS, Anagnostopoulos A, Dyer MJ, Catovsky D and Mellstedt H (1996) Humanized CD52 monoclonal antibody Campath-1H as first-line treatment in chronic lymphocytic leukemia. British Journal of Hematology 93: 151-153.

Reuter H, Wraight EP, Qasim FJ and Lockwood CM (1995) Management of vasculitis: the contribution of scintigraphic imaging to the evaluation of disease activity and classification. Quarterly Journal of Medicine 88: 509-516.

Riechmann L, Clark M, Waldmann H and Winter G (1988) Reshaping human antibodies for therapy. Nature 332: 323-327.

Treumann A, Lifely R, Schneider P and Ferguson MA) (1995) Primary structure of CD52. journal of Biological Chemistry 270: 6088-6099.

Xia M-Q, Hale G, Lifely MR et al (1993) Structure of the CAMPATH-1 antigen, a GPI-anchored glycoprotein which is an exceptionally good target for complement lysis. Biochemical Journal 29: 633-640.

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