Development

In 1948, American chemist Edward Calvin Kendall (1886-1972) and American physician Philip Showalter Hench (1896-1965) discovered a compound that had anti-inflammatory activity and reversed the symptoms of rheumatoid arthritis (a disease that causes painful joints). This compound, which they named cortisone, was a form of corticosteroid.

Their patient, a middle-aged woman with rheumatoid arthritis (RA), was suffering from severe pain and joint swelling. She was given a series of experimental cortisone injections over several weeks. When the treatment was finished, her symptoms had seemed to disappear. For their contribution to medicine—specifi-cally, their discoveries relating to the hormones of the adrenal cortex—Hench and Kendall, along with Polish-born Swiss chemist Tadeus Reichstein (1897-1996), were awarded the Nobel Prize in Physiology or Medicine in 1950.

In the 1950s, an American chemist synthesized cortisone, but its production involved a very expensive and lengthy procedure. By the end of the 1950s, a process was developed that made cortisone more easily in large quantities. Although corticosteroids were effective in treating various ailments involving inflammation, the reason why they worked was unknown. With further research, this was discovered in the 1980s.

Arthritis Relief and Prevention

Arthritis Relief and Prevention

This report may be oh so welcome especially if theres no doctor in the house Take Charge of Your Arthritis Now in less than 5-Minutes the time it takes to make an appointment with your healthcare provider Could you use some help understanding arthritis Maybe a little gentle, bedside manner in your battle for joint pain relief would be great Well, even if you are not sure if arthritis is the issue with you or your friend or loved one.

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