Mixed Connective Tissue Disease

Mixed connective tissue disease (MCTD) is a relatively rare syndrome with clinical features that overlap with systemic sclerosis, systemic lupus erythematosus, idiopathic inflammatory myopathies, and rheumatoid arthritis (Chapter 1). The typical clinical features are Raynaud's phenomenon, polyarthritis, myalgias, swelling of the hands, and esophageal dysfunction. Unlike systemic sclerosis, patients with MCTD may respond to corticosteroids. The primary clinical esophageal symptoms are heartburn and regurgitation, occurring in 24% to 48% of patients (16). Oropharyngeal dysphagia and/or esophageal dysphagia are common symptoms. Barium esophagram studies show findings similar to those in systemic sclerosis, mainly diminished esophageal peristalsis, and a dilated esophagus. Modified barium swallow studies may show oropharyngeal dysfunction similar to that seen in patients with polymyositis. Manometry is similar to systemic sclerosis; however, the LES pressures are usually not as diminished.

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Arthritis Relief and Prevention

Arthritis Relief and Prevention

This report may be oh so welcome especially if theres no doctor in the house Take Charge of Your Arthritis Now in less than 5-Minutes the time it takes to make an appointment with your healthcare provider Could you use some help understanding arthritis Maybe a little gentle, bedside manner in your battle for joint pain relief would be great Well, even if you are not sure if arthritis is the issue with you or your friend or loved one.

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