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Figure 1. CA1E with Con A as a ligand of AGP in sera of:

(a) a healthy individual

(b) an active rheumatoid arthritis patient (type II glycosylation changes)

(c) a patient with systemic lupus erthematosus with intercurrent infection (type I of glycosylation changes).

Figure 1. CA1E with Con A as a ligand of AGP in sera of:

(a) a healthy individual

(b) an active rheumatoid arthritis patient (type II glycosylation changes)

(c) a patient with systemic lupus erthematosus with intercurrent infection (type I of glycosylation changes).

Con A reactive variants/Con A non-reactive variant (B+C+D/A) Three AGP variants were observed in the sera of healthy individuals.

In our previous study (Sluzewska et al., 1996a), we have found various alterations of major microheterogeneity of AGP in 75% of patients during an acute depressive episode. Type I changes of glycosylation, consisting of high AGP levels and high values of AGP-RC, similar to those occurring in some acute inflammatory states were found in one third of depressed patients. Patients belonging to this group suffered a longer duration of the illness and of the last episode and were refractory to pharmacological treatment.

Type II changes of glycosylation, including high levels of AGP and low values of AGP-RC, similar to those occurring in chronic inflammatory states, were found in patients with a shorter duration of the last episode.

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Arthritis Joint Pain

Arthritis Joint Pain

Arthritis is a general term which is commonly associated with a number of painful conditions affecting the joints and bones. The term arthritis literally translates to joint inflammation.

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