References

Thyroid Factor

The Natural Thyroid Diet

Get Instant Access

Armitage, R.J. (1994). Tumor necrosis factor receptor superfamily members and their ligands. Curr. Opin. Immunol., 6, 407-413.

Blobel, G., and Dobberstein, B. (1975). Transfer to proteins across membranes. II. Reconstitutuion of functional rough microsomes from heterologous components. J. Cell. Biol., 67, 852-862.

Bretcher, P., and Cohn, M. (1970). A theory of self-non-self discrimination. Science, 169, 1042-1049.

Broll, K., Richter, G., Pauly, S., Hofstaedter, F., and Schwarz, H. (2001). CD137 expression in tumor vessel walls. High correlation with malignant tumors. Am. J. Clin. Pathol., 115, 543-549.

Chalupny, N.J., Peach, R., Hollenbaug, D., Ledbetter, J.A., Farr, A.G., and Aruffo, A. (1992). T cell activation molecule 4-1BB binds to extracellular matrix proteins. Proc. Natl. Acad. Sci., U.S.A., 89, 10360-10364.

Chu, N.R., DeBenedette, M.A., Stiernholm, B.J., Barber, B.H., and Watts, T.H. (1997). Role of IL-12 and 4-1BBL in cytokine production by CD28+ and CD28- T cells. J. Immunol., 158, 30813089.

Croft, M. (2003). Co-stimulatory members of TNFR family: keys to effective T cell immunity. Nat. Rev. Immunol., 3, 609-620.

DeBenedette, M.A., Shahinian, A., Mak, T.W., and Watts T.H. (1997). Co-stimulation of CD28-T lymphocytes by 4-1BB ligand. J. Immunol., 158, 551-559.

DeBenedette, M.A., Wen, T., Bachmann, M.F., Ohashi, P.M., Barber, B.H., Stocking, K.L., Peschon, J.J., and Watts, T.H. (1999). Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus. J. Immunol., 163, 4833-4841.

Diehl, L., vanMierlo, G.J., den Boer, A.T., vanderVoort, E., Fransen, M., vanBostelen, L., Krimpenfort, P., Melief, C.J., Mittler, R., Toes, R.E., and Offringa, R. (2002). In vivo triggering through 4-1BB enables Th-independent priming of CTL in the presence of an intact CD28 costimulatory pathway. J Immunol., 168, 3755-3762.

Foell, J., Strahotin, S., O'Neil, S.P., McClausland, M.M., Suwyn, C., Haber, M., Chander, P.N., Bapat, A.S., Yan, X.J., Chiorazzi, N., Hoffmann, M.K., and Mittler, R.S. (2003). CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice. J. Clin. Invest., 111, 1505-1518.

Futugawa, T., Akiba, H., Kodama, T., Takeda, K., Hosoda, Y., Yagita, H., and Okukura, K. (2002). Expression and function of 4-1BB and 4-1BBL on murine dendritic cells. Int. Immunol., 14, 275-276.

Garni-Wagner, B.A., Lee, Z.H., Kim, Y.J., Wilde, C.E., Kang, C.Y., and Kwon, B.S. (1996). 4-1BB is expressed on CD45 RAhi ROhi translational T cells in humans. Cell. Immunol., 169, 91-98.

Goh, C.R., and Porter, A.G. (1990). Structural and functional domains in human tumor necrosis factors. Protein Eng., 4, 385-389.

Goodwin, R.G., Din, W.S., Davis-Smith, T., Anderson, D.M., Gimpel, S.D., Sato, T.A., Maliszewski, C.R., Brannan, C.I., Copeland, N.G., Jenkins, N.A., Farrah, T., Armitage, R.J., Fanslow, W.C., and Smith, C.A. (1993). Molecular cloning of a ligand for the inducible T cell gene 4-1BB: A member of an emerging family of cytokines with homology to tumor necrosis factor. Eur. J. Immunol., 23, 2631-2641.

Gramaglia, I., Cooper, D., Miner, K.T., Kwon, B.S., and Croft, M. (2000). Co-stimulation of antigen-specific CD4 T cells by 4-1BB ligand. Eur. J. Immunol., 30, 392-402.

Halstead, E.S., Mueller, Y.M., Altman, J.D., and Katsikis, P.D. (2002). In vivo stimulation of CD137 broadens primary antiviral CD8+ T cells responses. Nat. Immunol., 3, 536-541.

Hurtado, J.C., Kim, Y.J., and Kwon, B.S. (1997). Signals through 4-1BB are costimulatory to previously activated splenic T cells and inhibit activation-induced cell death. J. Immunol., 158, 26002609.

Jung, H.W., Choi, S.W., Choi, J.I., and Kwon, B.S. (2004). Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis. Exp. Mol. Med., 36, 13-22.

Kienzel, G., and von Kempis, J. (2000). CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes. Int. Immunol., 12, 73-82.

Kim, Y.J., Kim, S.H., Mantel, P., and Kwon, B.S. (1998). Human 4-1BB regulates CD28 co-stimulation to promote Th1 cells responses. Eur. J. Immunol., 28, 881-889.

Kim, K.M., Kim, H.W., Kim, J.O., Baek, K.M., Kim, J.G., and Kang, C.Y. (2002). Induction of 4-1BB (CD137) expression by DNA damaging agents in human T lymphocytes. Immunology, 107, 472-479.

Kim, J.O., Kim, H.W., Baek, K.M., and Kang, C.Y. (2003). NF-kB and AP-1 regulate activation-dependent CD137 (4-1BB) expression in T cells. FEBSLett, 541, 163-170.

Kim, J., Choi, W.S., La, S., Suh, J.H., Kim, B.S., Cho, H.R., Kwon, B.S., and Kwon, B. (2004). Stimulation with 4-1BB (CD137) inhibits chronic graft-versus-host disease by inducing activation-induced cell death of donor CD4+ T cells. Blood, 105, 2206-2213.

Kwon, B.S., Kim, C.S., Prystowski, M.B., Lancki, D.W., Sabath, D.E., Pan, J.L., and Weissman, S.M. (1987). Isolation and initial characterization of multiple species of T lymphocyte subset cDNA clones. Proc. Natl. Acad. Sci. U.S.A., 84, 2896-2900.

Kwon, B.S., and Weissman, S.M. (1989). cDNA sequences of two inducible T cell genes. Proc. Natl. Acad. Sci. U.S.A., 86, 1963-1967.

Kwon, B.S., Kestler, D.P., Eshhar, Z., Oh, K., and Wakulchik, M. (1989). Expression characteristics of two potential T cell mediator genes. Cell. Immunol., 121, 414—422.

Kwon, B.S., Hurtado, J.C., Lee, Z.H., Kwack, K.B., Seo, S.K., Choi, B.K., Koller, B.H., Wolisi, G., Broxmeyer, H.E., and Vinay, D.S. (2002). Immune responses in 4-1BB (CD137)-deficient mice. J. Immunol., 168, 5483-5490.

Laderach, D., Wesa, A., and Galy, A. (2003). 4-1BB ligand is regulated on human dendritic cells and induces the production of IL-12. Cell. Immunol., 226, 37-44.

Langstein, J., Michel, J., Fritsche, J., Kreutz, M., Anderson, R., and Schwarz, H. (1998). CD137 (ILA/4-1BB), a member of the TNF receptor family induces monocyte activation via bidirectional signaling. J Immunol., 160, 2488-2494.

Lim, H.Y., Kim, K.K., Zhou, F.C., Yoon, J.W., Hill, J.M., and Kwon, B.S. (2002). 4-1BB-like molecule is expressed in islet-infiltrating mononuclear cells and in the gray matter of the brain. Cell. Biol. Int., 26, 271-278.

Lindstedt, M., Johansson-Lindbom, B., and Borrebaeck, C.A. (2003). Expression of CD137 (4-1BB) on human follicular dendritic cells. Scand. J. Immunol., 5, 305-310.

Maerten, T., Geboes, K., De Hertogh, G., Shen, C., Cadot, P., Bullens, D.M., Van Assche, G., Penninckx, F., Rutgeerts, P., and Cueppens, J.L. (2004). Functional expression of 4-1BB (CD137) in the inflammatory tissue in Crohn's disease. Clin. Immunol., 112, 239-246.

McHugh, R.S., Matthew, J.W., Piccirillo, C.A., Young, D.A., Shevach, E.M., Collins, M., and Byrne, M.C. (2002). CD4+CD25+ immunoregulatory T cells: Gene expression analysis reveals a functional role forthe glucocorticoid-induced TNF receptor. Immunity, 16, 311-323.

Melero, I., Shuford, W.W., Newby, S.A., Aruffo, A., Ledbetter, J.A., Hellstrom, K.E., Mittler, R.S., and Chen, L. (1997). Monoclonal antibodies against 4-1BB T cell activation molecule eradicate established tumors. Nat. Med., 3, 682-685.

Melero, I., Johnston, J.V, Shuford, W.W., Mittler, R.S., and Chen, L. (1998). NK1.1 cellsexpress 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell. Immunol., 190, 167-172.

Mittler, R.S., Bailey, T.S., Klussman, K., Trailsmith, M.D., and Hoffmann, M.K. (1999). Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy. J Exp Med., 190, 1535-1540.

Pollok, K.E., Kim, Y.J., Zhou, Z., Hurtado, J., Kim, K.K., Pickard, R.T., and Kwon, B.S. (1993). Inducible T cell antigen 4-1BB. Analysis of expression and function. J Immunol., 150, 771-781.

Pollok, K.E., Kim, Y.J., Hurtado, J.C., Zhou, Z., Kim, K.K., and Kwon, B.S. (1994). 4-1BB T cell antigen binds to mature B cells and macrophages and co-stimulates anti-|i-primed splenic B cells. Eur. J. Immunol., 24, 367-374.

Salih, H.R., Schmetzer, H.M., Burke, C., Straling, G.C., Dunn, R., Pelka-Fleiscischer, R., Nuessler, V., and Kiener, P.A. (2001). Soluble CD137 (4-1BB) ligand is released following leukocyte activation and is found in sera of patients with hematological malignancies. J. Immunol., 167, 4059-4066.

Saoulli, K., Lee, S.Y., Cannons, J.L., Yeh, W.C., Santana, A., Goldstein, M.D., Bangia, DeBenedette, M.A., Mak, T.W., Choi, Y., and Watts, T.H. (1998). J. Exp. Med, 187, 1849-1862.

Schwartz, R.R. (1990). A cell culture model for T lymphocyte clonal anergy. Science, 248, 1349-1356.

Schwarz, H., Tuckwell, J., and Lotz, M. (1993). A receptor induced by lymphocyte activation (ILA); a new member of the human nerve growth factor/tumor necrosis factor receptor family. Gene, 134, 295-298.

Schwarz, H., Valbracht, J., Tuckwell, J., von Kempis, J., and Lotz, M. (1995). ILA, the human 4-1BB homologue, is inducible in lymphoid and other cell lineages. Blood, 85, 1043-1052.

Seko, Y., Takahashi, N., Oshima, H., Shimozato, O., Akiba, H., Takeda, K., Kobata, T., Yagita, H., Okumura, K., Azuma, M., and Nagai, R. (2001). Expression of tumor necrosis factor (TNF) ligand superfamily costimulatory molecules CD30L, CD27L, 0X40L, and 4-1BBL in murine hearts with acute myocarditis caused by coxsackievirus B3. J. Pathol., 195, 593-603.

Seko, H., Ishiyama, S., Nishikawa, T., Kasajima, T., Hiroe, M., Suzuki, S., Ishiwata, S., Kawai, S., Tanaka, Y., Azuma, M., Kobata, T., Yagita, H., Okumura, K., and Nagai, R. (2002). Expression of tumor necrosis factor ligand superfamily costimulatory molecules CD27L, CD30L, 0X40L, and 4-1BBL in the heart of patients with acute myocarditis and dilated cardiomyopathy. Cardiovasc. Pathol., 11, 166-170.

Seko, Y., Sugishita, K., Sato, O., Takagi, A., Tada, Y., Matsuo, H., Yagita, H., Okumura, K., and Nagai, R. (2004). Expression of costimulatory molecules (4-1BBLandFas) and major histocompatibility class I chain-related A (MICA) in aortic tissue with Takayasu's arteritis. J. Vasc. Res., 41, 84—90.

Seo, S.K., Choi, J.H., Kim, Y.H., Kang, W.J., Park, H.Y., Suh, J.H., Choi, B.K., Vinay, D.S., and Kwon, B.S. (2004). 4-1BB-mediated immunotherapy of rheumatoid arthritis. Nat. Med., 10, 1088-1094.

Shuford, W.W., Klussman, K., Tritchler, D.D., Loo, D.T., Chalupny, J., Siadak, A.W., Brown, T.J., Emswiler, J., Raecho, H., Larsen, C.P., Pearson, T.C., Ledbetter, J.A., Aruffo, A., and Mittler, R.S. (1997). 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell response. J Exp Med., 186, 47-55.

Smith, C.A., Farrah, T., and Goodwin, R.G. (1994). The TNF receptor superfamily of cellular and viral proteins; activation, co-stimulation, and death. Cell, 76, 959-962.

Summers, K.L., Hock, B.D., McKenzie, J.L., and Hart, D.N. (2001). Phenotypic characterization of five dendritic cell subsets in human tonsils. Am. J. Pathol., 159, 285-295.

Sun, Y., Lin, X., Chen, H.M., Wu, Q., Subudhi, S.K., Chen, L., and Fu, Y.X. (2002). Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis. J. Immunol., 168, 1457-1465.

Takahashi, T., Mittler, R.S., and Vella, A.T. (1999). 4-1BB is a bona fide CD8 T cell survival signal. J Immunol., 162, 5037-5040.

Vinay, D.S., and Kwon, B.S. (1998). Role of4-1BB in immune responses. Sem. Immunol., 10, 481-489.

Vinay, D.S., Choi, B.K., Bae, J.S., Kim, W.Y., Gebhardt, B.M., andKwon, B.S. (2004). CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses. J. Immunol., 173, 4218-4229.

Von Heijne, G. (1983). Patterns of amino acids near signal-sequence cleavage sites. Eur. J. Biochem., 133, 17-21.

Wan, Y.L., Zheng, S.S., Zhao, Z.C., Li, M.W., Jia, C.K., and Zhang, H. (2004). Expression of co-stimulator 4-1BB molecule in hepatocellular carcinoma and adjacent non-tumor liver tissue, and its possible role in tumor immunity. World J. Gastroenterol., 10, 195-199.

Wilcox, R.A., Chapoval, A.I., Gorski, K.S., Otsuji, M., Shin, T., Flies, D.B., Tamada, K., Mittler, R.S., Tsuchiya, H., Pardoll, D.M., and Chen, L. (2002). Expression of functional CD137 receptor by dendritic cells. J. Immunol., 168, 4262-4267.

Yamada-Okabe, T., Satoh, and Yamade-Okabe, H. (2003). Thyroid hormone induces the expression of 4-1BB and activation of caspases in thyroid hormone receptor-dependent manner. Eur. J. Biochem., 270, 3064-3073.

Yndestad, A., Damas, J.K., Geir Eiken, H., Holm, T., Hauh, T., Simonsen, S., Froland, S.S., Gullestad, L., and Aukrust, P. (2002). Increased gene expression of tumor necrosis factor superfamily ligands in peripheral blood mononuclear cells during chronic heart failure. Cardiovasc. Res., 54,175-182.

Zhang, H., Merchant, M.S., Chua, K.S., Khanna, C., Helman, L.J., Telford, B., Ward, Y., Summers, J., Toretsky, J., Thomas, E.K., June, C.H., and Mackall, C.L. (2003). Tumor expression of 4-1BB ligand sustains tumor lytic T cells. Cancer Biol. Ther., 2, 579-586.

Zhou, Z., Kim, S.H., Hurtado, J.C., Lee, Z., Kim, K.K., Pollok, K.E., and Kwon, B.S. (1995). Characterization of human homologue of 4-1BB and its ligand. Immunol. Lett., 45, 67-73.

Was this article helpful?

0 0
Arthritis Relief and Prevention

Arthritis Relief and Prevention

This report may be oh so welcome especially if theres no doctor in the house Take Charge of Your Arthritis Now in less than 5-Minutes the time it takes to make an appointment with your healthcare provider Could you use some help understanding arthritis Maybe a little gentle, bedside manner in your battle for joint pain relief would be great Well, even if you are not sure if arthritis is the issue with you or your friend or loved one.

Get My Free Ebook


Post a comment