Celery has been found to have anti-inflammatory activity, with suppression of carrageenan-induced paw oedema observed in rats (Al-Hindawi et al 1989). Several constituents show anti-inflammatory activity, such as apigenin, eugenol, ferulic acid, luteolin and bergapton (Duke 2003). Studies in rats suggest that some celery seed extracts are highly effective in suppressing experimental arthritis without exhibiting any gastrotoxicity (Whitehouse et al 1999). Further in vivo studies suggest that celery seed extracts were gastroprotective for NSAID gastropathy and that this effect is mediated through non-prostaglandin mechanisms (Whitehouse et al 2001).
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