Gallium maltolate

Gallium maltolate GM Figure 14.2) is an orally active complex that is moderately soluble in both aqueous and lipidie solutions (octanol water partition coefficient of 0.41(8)) and is stable over a pH range of about 5.5-8.0.126 The compound has shown oral gallium bioavailability of at least 25-57 in healthy human subjects, with roughly linear absorption and elimination kinetics following single doses of 100-500 mg and an average maximum serum gallium level (Cmax) of 569(17) ng ml at the 500-mg...

Gold therapy for rheumatoid arthritis

End Stage Lyme Disease Symptoms

It is generally agreed that RA is an inflammatory disease, of unknown causation, and one that is manifested, sometimes chronically, particularly in the peripheral joints of the body. The well-recognized symptoms of the disease, arising from inflammation, are the swellings of the joints and the incumbent physical disability and pain. Inflammation occurs first in the synovial membrane surrounding the joints and soon spreads to the synovium with progression of the disease. This has the result of...